SCOP 1.73: Domain d1mrdl1: 1mrd L:1-108

Lineage for d1mrdl1 (1mrd L:1-108)

1. Root: SCOP 1.73

2. Class b: All beta proteins [48724] (165 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (27 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (29 proteins)

6. Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (14 species)
   VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 1.1 [TaxId:10090] [88524] (127 PDB entries)

8. Domain d1mrdl1: 1mrd L:1-108 [20016]
   Other proteins in same PDB: d1mrdh1, d1mrdh2, d1mrdl2
   part of Fab Jel 103
   complexed with idp, imd, zn

Details for d1mrdl1

PDB Entry: 1mrd, 2.3 Å

PDB Description: preparation, characterization and crystallization of an antibody fab fragment that recognizes rna. crystal structures of native fab and three fab-mononucleotide complexes

PDB Compounds: (L:) igg2b-kappa jel103 fab (light chain)

SCOP Domain Sequences for d1mrdl1:

Sequence; same for both SEQRES and ATOM records:

>d1mrdl1 b.1.1.1 (L:1-108) Immunoglobulin light chain kappa variable domain, VL-kappa {Mouse (Mus musculus), cluster 1.1 [TaxId: 10090]}
dvvmtqtplslpvslgdqasiscrssqslvhsngntylhwylqkpgqspklliykvsnrf
sgvpdrfsgsgsgtdftlkisrveaedlgvyfcsqsthvprtfgggtkleikr

Timeline for d1mrdl1:

• d1mrdl1 first appeared (with stable ids) in SCOP 1.55
  
• d1mrdl1 appears in SCOP 1.71
  
• d1mrdl1 appears in SCOP 1.75
  
• d1mrdl1 appears in the current release, SCOPe 2.08