Lineage for d1eapa1 (1eap A:1-107)

  1. Root: SCOPe 2.08
  2. 2739516Class b: All beta proteins [48724] (180 folds)
  3. 2739517Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2739518Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2739519Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)
  6. 2740696Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (16 species)
    VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 2741296Species Mouse (Mus musculus), cluster 4 [TaxId:10090] [88531] (231 PDB entries)
    Uniprot P01645 1-106 # 95% sequense identity; KV5L_MOUSE Ig kappa chain V-V region HP 93G7 ! SQ NA # natural chimera; best hits are: Uniprot P01637 (Ig kappa chain V-V region T1) and Uniprot P01837 (Ig kappa chain C region) ! SQ NA # humanized antibody ! SQ NA # part of Fab 28 against HIV-1 RT ! Uniprot P01642 21-115 # ! KV5I_MOUSE Ig kappa chain V-V region L7 precursor
  8. 2741411Domain d1eapa1: 1eap A:1-107 [20014]
    Other proteins in same PDB: d1eapa2, d1eapb1, d1eapb2
    part of Fab 17E8
    complexed with hep

Details for d1eapa1

PDB Entry: 1eap (more details), 2.4 Å

PDB Description: crystal structure of a catalytic antibody with a serine protease active site
PDB Compounds: (A:) igg2b-kappa 17e8 fab (light chain)

SCOPe Domain Sequences for d1eapa1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1eapa1 b.1.1.1 (A:1-107) Immunoglobulin light chain kappa variable domain, VL-kappa {Mouse (Mus musculus), cluster 4 [TaxId: 10090]}
dieltqspsslsaslggkvtitckasqdikkyigwyqhkpgkgprllihytstllpgips
rfrgsgsgrdysfsisnleggdiatyyclqyynlrtfgggtkleik

SCOPe Domain Coordinates for d1eapa1:

Click to download the PDB-style file with coordinates for d1eapa1.
(The format of our PDB-style files is described here.)

Timeline for d1eapa1:

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Domains from same chain:
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d1eapa2