Lineage for d3meca2 (3mec A:430-552)

  1. Root: SCOPe 2.05
  2. 1815291Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 1857400Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
    3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest
  4. 1859086Superfamily c.55.3: Ribonuclease H-like [53098] (15 families) (S)
    consists of one domain of this fold
  5. 1859087Family c.55.3.1: Ribonuclease H [53099] (5 proteins)
  6. 1859138Protein HIV RNase H (Domain of reverse transcriptase) [53105] (3 species)
  7. 1859139Species Hiv-1 m:b_hxb2r [TaxId:11706] [224897] (8 PDB entries)
  8. 1859144Domain d3meca2: 3mec A:430-552 [199830]
    Other proteins in same PDB: d3meca1, d3mecb_
    automated match to d1c1ba1
    complexed with 65b, so4

Details for d3meca2

PDB Entry: 3mec (more details), 2.3 Å

PDB Description: HIV-1 Reverse Transcriptase in Complex with TMC125
PDB Compounds: (A:) p66 Reverse transcriptase

SCOPe Domain Sequences for d3meca2:

Sequence; same for both SEQRES and ATOM records: (download)

>d3meca2 c.55.3.1 (A:430-552) HIV RNase H (Domain of reverse transcriptase) {Hiv-1 m:b_hxb2r [TaxId: 11706]}
ekepivgaetfyvdgaanretklgkagyvtnrgrqkvvtltdttnqktelqaiylalqds
glevnivtdsqyalgiiqaqpdqseselvnqiieqlikkekvylawvpahkgiggneqvd
klv

SCOPe Domain Coordinates for d3meca2:

Click to download the PDB-style file with coordinates for d3meca2.
(The format of our PDB-style files is described here.)

Timeline for d3meca2:

View in 3D
Domains from same chain:
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d3meca1
View in 3D
Domains from other chains:
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d3mecb_