Lineage for d1a7ph_ (1a7p H:)

  1. Root: SCOPe 2.05
  2. 1755445Class b: All beta proteins [48724] (176 folds)
  3. 1755446Fold b.1: Immunoglobulin-like beta-sandwich [48725] (31 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 1755447Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 1755448Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)
  6. 1755653Protein Immunoglobulin heavy chain variable domain, VH [88543] (21 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 1756427Species Mouse (Mus musculus), cluster 5 [TaxId:10090] [88555] (36 PDB entries)
  8. 1756442Domain d1a7ph_: 1a7p H: [19951]
    Other proteins in same PDB: d1a7pl_
    part of Fv D1.3
    complexed with acy; mutant

Details for d1a7ph_

PDB Entry: 1a7p (more details), 2.01 Å

PDB Description: fv fragment of mouse monoclonal antibody d1.3 (balb/c, igg1, k) engineered mutant pro95l->ser on variant chain l glu81->asp and chain h leu312->val
PDB Compounds: (H:) igg1-kappa d1.3 fv (heavy chain)

SCOPe Domain Sequences for d1a7ph_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1a7ph_ b.1.1.1 (H:) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 5 [TaxId: 10090]}
qvqlqesgpglvapsqslsitctvsgfsltgygvnwvrqppgkglewlgmiwgdgntdyn
salksrlsiskdnsksqvflkmnslhtddtaryycarerdyrldywgqgttvtvss

SCOPe Domain Coordinates for d1a7ph_:

Click to download the PDB-style file with coordinates for d1a7ph_.
(The format of our PDB-style files is described here.)

Timeline for d1a7ph_: