SCOPe 2.02: Domain d1a7rh_: 1a7r H:

Lineage for d1a7rh_ (1a7r H:)

1. Root: SCOPe 2.02

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)

6. Protein Immunoglobulin heavy chain variable domain, VH [88543] (21 species)
   VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 5 [TaxId:10090] [88555] (36 PDB entries)

8. Domain d1a7rh_: 1a7r H: [19945]
   Other proteins in same PDB: d1a7rl_
   part of Fv D1.3

Details for d1a7rh_

PDB Entry: 1a7r, 2.01 Å

PDB Description: fv fragment of mouse monoclonal antibody d1.3 (balb/c, igg1, k) variant chain l glu81->asp

PDB Compounds: (H:) igg1-kappa d1.3 fv (heavy chain)

SCOPe Domain Sequences for d1a7rh_:

Sequence; same for both SEQRES and ATOM records:

>d1a7rh_ b.1.1.1 (H:) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 5 [TaxId: 10090]}
qvqlqesgpglvapsqslsitctvsgfsltgygvnwvrqppgkglewlgmiwgdgntdyn
salksrlsiskdnsksqvflkmnslhtddtaryycarerdyrldywgqgttltvss

Timeline for d1a7rh_:

• d1a7rh_ first appeared (with stable ids) in SCOP 1.55
  
• d1a7rh_ appears in SCOPe 2.01
  
• d1a7rh_ appears in SCOPe 2.03
  
• d1a7rh_ appears in the current release, SCOPe 2.08