Lineage for d1vfba_ (1vfb A:)

  1. Root: SCOPe 2.01
  2. 929298Class b: All beta proteins [48724] (174 folds)
  3. 929299Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 929300Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 929301Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)
  6. 930396Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (16 species)
    VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 930985Species Mouse (Mus musculus), cluster 4 [TaxId:10090] [88531] (184 PDB entries)
    Uniprot P01645 1-106 # 95% sequense identity; KV5L_MOUSE Ig kappa chain V-V region HP 93G7 ! SQ NA # natural chimera; best hits are: Uniprot P01637 (Ig kappa chain V-V region T1) and Uniprot P01837 (Ig kappa chain C region) ! SQ NA # humanized antibody ! SQ NA # part of Fab 28 against HIV-1 RT ! Uniprot P01642 21-115 # ! KV5I_MOUSE Ig kappa chain V-V region L7 precursor
  8. 930997Domain d1vfba_: 1vfb A: [19930]
    Other proteins in same PDB: d1vfbb_, d1vfbc_
    part of Fv D1.3

Details for d1vfba_

PDB Entry: 1vfb (more details), 1.8 Å

PDB Description: bound water molecules and conformational stabilization help mediate an antigen-antibody association
PDB Compounds: (A:) igg1-kappa d1.3 fv (light chain)

SCOPe Domain Sequences for d1vfba_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1vfba_ b.1.1.1 (A:) Immunoglobulin light chain kappa variable domain, VL-kappa {Mouse (Mus musculus), cluster 4 [TaxId: 10090]}
divltqspaslsasvgetvtitcrasgnihnylawyqqkqgkspqllvyytttladgvps
rfsgsgsgtqyslkinslqpedfgsyycqhfwstprtfgggtkleik

SCOPe Domain Coordinates for d1vfba_:

Click to download the PDB-style file with coordinates for d1vfba_.
(The format of our PDB-style files is described here.)

Timeline for d1vfba_: