SCOPe 2.01: Domain d1vfab_: 1vfa B:

Lineage for d1vfab_ (1vfa B:)

1. Root: SCOPe 2.01

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)

6. Protein Immunoglobulin heavy chain variable domain, VH [88543] (22 species)
   VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 5 [TaxId:10090] [88555] (36 PDB entries)

8. Domain d1vfab_: 1vfa B: [19929]
   Other proteins in same PDB: d1vfaa_
   part of Fv D1.3

Details for d1vfab_

PDB Entry: 1vfa, 1.8 Å

PDB Description: bound water molecules and conformational stabilization help mediate an antigen-antibody association

PDB Compounds: (B:) igg1-kappa d1.3 fv (heavy chain)

SCOPe Domain Sequences for d1vfab_:

Sequence; same for both SEQRES and ATOM records:

>d1vfab_ b.1.1.1 (B:) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 5 [TaxId: 10090]}
qvqlqesgpglvapsqslsitctvsgfsltgygvnwvrqppgkglewlgmiwgdgntdyn
salksrlsiskdnsksqvflkmnslhtddtaryycarerdyrldywgqgttltvss

Timeline for d1vfab_:

• d1vfab_ first appeared (with stable ids) in SCOP 1.55
  
• d1vfab_ appears in SCOP 1.75
  
• d1vfab_ appears in SCOPe 2.02
  
• d1vfab_ appears in the current release, SCOPe 2.08