Class b: All beta proteins [48724] (174 folds) |
Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies) sandwich; 7 strands in 2 sheets; greek-key some members of the fold have additional strands |
Superfamily b.1.1: Immunoglobulin [48726] (5 families) |
Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins) |
Protein Immunoglobulin heavy chain variable domain, VH [88543] (21 species) VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species |
Species Mouse (Mus musculus), cluster 3.2 [TaxId:10090] [88552] (177 PDB entries) Uniprot P01756 1-117 # 78% sequense identity; HV12_MOUSE Ig heavy chain V region MOPC 104E ! SQ NA # humanized antibody ! Uniprot P01750 # HV06_MOUSE Ig heavy chain V region 102 precursor ! Uniprot P01750 20-116 # ! HV06_MOUSE Ig heavy chain V region 102 precursor |
Domain d1figh1: 1fig H:1-113 [19923] Other proteins in same PDB: d1figh2, d1figl1, d1figl2 part of catalytic antibody 1F7 with chorismate mutase activity complexed with tsa |
PDB Entry: 1fig (more details), 3 Å
SCOPe Domain Sequences for d1figh1:
Sequence; same for both SEQRES and ATOM records: (download)
>d1figh1 b.1.1.1 (H:1-113) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 3.2 [TaxId: 10090]} dvqlqqsgpelekpgasvkisckasgfslpghninwivqrngkslewignidpyyggtnf npkfkgkatltvdkssstlymhltslqsedsavyycarrrdgnygftywgqgtlvtvsa
Timeline for d1figh1: