SCOPe 2.04: Domain d3c6ua2: 3c6u A:0-429

Lineage for d3c6ua2 (3c6u A:0-429)

1. Root: SCOPe 2.04

2. Class e: Multi-domain proteins (alpha and beta) [56572] (68 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (7 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.2: Reverse transcriptase [56686] (3 proteins)

6. Protein HIV-1 reverse transcriptase [56689] (3 species)

7. Species Hiv-1 m:b_hxb2r [TaxId:11706] [190022] (22 PDB entries)

8. Domain d3c6ua2: 3c6u A:0-429 [199172]
   Other proteins in same PDB: d3c6ua3
   automated match to d1bqna2
   protein/DNA complex; protein/RNA complex; complexed with m22

Details for d3c6ua2

PDB Entry: 3c6u, 2.7 Å

PDB Description: Crystal Structure of HIV Reverse Transcriptase in complex with inhibitor 22

PDB Compounds: (A:) reverse transcriptase

SCOPe Domain Sequences for d3c6ua2:

Sequence; same for both SEQRES and ATOM records:

>d3c6ua2 e.8.1.2 (A:0-429) HIV-1 reverse transcriptase {Hiv-1 m:b_hxb2r [TaxId: 11706]}
spispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntp
vfaikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvp
ldedfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiv
iyqymddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkw
tvqpivlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteea
elelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrg
ahtndvkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvnt
pplvklwyql

Timeline for d3c6ua2:

• d3c6ua2 first appeared in SCOPe 2.03
  
• d3c6ua2 appears in SCOPe 2.05
  
• d3c6ua2 appears in the current release, SCOPe 2.08