SCOP 1.69: Domain d1flrl1: 1flr L:1-112

Lineage for d1flrl1 (1flr L:1-112)

1. Root: SCOP 1.69

2. Class b: All beta proteins [48724] (144 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (23 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (27 proteins)

6. Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (14 species)
   VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 1.1 [TaxId:10090] [88524] (126 PDB entries)

8. Domain d1flrl1: 1flr L:1-112 [19904]
   Other proteins in same PDB: d1flrh1, d1flrh2, d1flrl2
   part of Fab 4-4-20

Details for d1flrl1

PDB Entry: 1flr, 1.85 Å

PDB Description: 4-4-20 fab fragment

SCOP Domain Sequences for d1flrl1:

Sequence; same for both SEQRES and ATOM records:

>d1flrl1 b.1.1.1 (L:1-112) Immunoglobulin light chain kappa variable domain, VL-kappa {Mouse (Mus musculus), cluster 1.1}
dvvmtqtplslpvslgdqasiscrssqslvhsngntylrwylqkpgqspkvliykvsnrf
sgvpdrfsgsgsgtdftlkisrveaedlgvyfcsqsthvpwtfgggtkleik

Timeline for d1flrl1:

• d1flrl1 first appeared (with stable ids) in SCOP 1.55
  
• d1flrl1 appears in SCOP 1.67
  
• d1flrl1 appears in SCOP 1.71
  
• d1flrl1 appears in the current release, SCOPe 2.08