SCOPe 2.03: Domain d2xwtb1: 2xwt B:2-107

Lineage for d2xwtb1 (2xwt B:2-107)

1. Root: SCOPe 2.03

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.0: automated matches [191470] (1 protein)
   not a true family

6. Protein automated matches [190740] (23 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187920] (336 PDB entries)

8. Domain d2xwtb1: 2xwt B:2-107 [198666]
   Other proteins in same PDB: d2xwtb2, d2xwtc_
   automated match to d2j6el1
   complexed with nag

Details for d2xwtb1

PDB Entry: 2xwt, 1.9 Å

PDB Description: crystal structure of the tsh receptor in complex with a blocking type tshr autoantibody

PDB Compounds: (B:) thyroid blocking human autoantibody k1-70 light chain

SCOPe Domain Sequences for d2xwtb1:

Sequence; same for both SEQRES and ATOM records:

>d2xwtb1 b.1.1.0 (B:2-107) automated matches {Human (Homo sapiens) [TaxId: 9606]}
svltqppsvsaapgqkvtiscsgsssdigsnyvswyqqfpgtapklliydnnkrpsaipd
rfsgsksgtsatlgitglqtgdeadyycgtwdsrlgiavfgggtqltvlg

Timeline for d2xwtb1:

• d2xwtb1 is new in SCOPe 2.03-stable
  
• d2xwtb1 appears in SCOPe 2.04
  
• d2xwtb1 appears in the current release, SCOPe 2.08