SCOPe 2.07: Domain d2vh6b_: 2vh6 B:

Lineage for d2vh6b_ (2vh6 B:)

1. Root: SCOPe 2.07

2. Class g: Small proteins [56992] (98 folds)

3. Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
   disulfide-bound fold; contains beta-hairpin with two adjacent disulfides

4. Superfamily g.3.11: EGF/Laminin [57196] (8 families)

5. Family g.3.11.1: EGF-type module [57197] (23 proteins)

6. Protein Factor X, N-terminal module [57205] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [57206] (85 PDB entries)
   Uniprot P00742 127-178

8. Domain d2vh6b_: 2vh6 B: [198444]
   Other proteins in same PDB: d2vh6a_
   automated match to d1lpga_
   complexed with gsv

Details for d2vh6b_

PDB Entry: 2vh6, 1.95 Å

PDB Description: structure and property based design of factor xa inhibitors: pyrrolidin-2-ones with biaryl p4 motifs

PDB Compounds: (B:) activated factor xa light chain

SCOPe Domain Sequences for d2vh6b_:

Sequence; same for both SEQRES and ATOM records:

>d2vh6b_ g.3.11.1 (B:) Factor X, N-terminal module {Human (Homo sapiens) [TaxId: 9606]}
trklcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtle

Timeline for d2vh6b_:

• d2vh6b_ first appeared in SCOPe 2.03
  
• d2vh6b_ appears in SCOPe 2.06
  
• d2vh6b_ appears in the current release, SCOPe 2.08