SCOP 1.65: Domain d1igfj1: 1igf J:1-113

Lineage for d1igfj1 (1igf J:1-113)

1. Root: SCOP 1.65

2. Class b: All beta proteins [48724] (126 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (20 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (21 proteins)

6. Protein Immunoglobulin heavy chain variable domain, VH [88543] (19 species)
   VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogeneous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 2.2 [TaxId:10090] [88550] (47 PDB entries)

8. Domain d1igfj1: 1igf J:1-113 [19815]
   Other proteins in same PDB: d1igfh2, d1igfj2, d1igfl1, d1igfl2, d1igfm1, d1igfm2
   part of Fab B13I2
   complexed with nag

Details for d1igfj1

PDB Entry: 1igf, 2.8 Å

PDB Description: crystal structures of an antibody to a peptide and its complex with peptide antigen at 2.8 angstroms

SCOP Domain Sequences for d1igfj1:

Sequence; same for both SEQRES and ATOM records:

>d1igfj1 b.1.1.1 (J:1-113) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 2.2}
evqlvesggdlvkpggslklscaasgftfsrcamswvrqtpekrlewvagissggsytfy
pdtvkgrfiisrnnarntlslqmsslrsedtaiyyctryssdpfyfdywgqgttltvss

Timeline for d1igfj1:

• d1igfj1 first appeared (with stable ids) in SCOP 1.55
  
• d1igfj1 appears in SCOP 1.63
  
• d1igfj1 appears in SCOP 1.67
  
• d1igfj1 appears in the current release, SCOPe 2.08