SCOPe 2.07: Domain d1hild1: 1hil D:1-112

Lineage for d1hild1 (1hil D:1-112)

Root: SCOPe 2.07
Class b: All beta proteins [48724] (178 folds)
Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
sandwich; 7 strands in 2 sheets; greek-key
some members of the fold have additional strands
Superfamily b.1.1: Immunoglobulin [48726] (5 families)
Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)

Protein Immunoglobulin heavy chain variable domain, VH [88543] (22 species)
VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species

Species Mouse (Mus musculus), cluster 2.2 [TaxId:10090] [88550] (61 PDB entries)
Uniprot P01811 # HV41_MOUSE (P01811) Ig heavy chain V region UPC10
Domain d1hild1: 1hil D:1-112 [19789]
Other proteins in same PDB: d1hila1, d1hila2, d1hilb2, d1hilc1, d1hilc2, d1hild2
part of Fab 17/9

Details for d1hild1

PDB Entry: 1hil (more details), 2 Å

PDB Description: structural evidence for induced fit as a mechanism for antigen-antibody recognition

PDB Compounds: (D:) igg2a-kappa 17/9 fab (heavy chain)

SCOPe Domain Sequences for d1hild1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1hild1 b.1.1.1 (D:1-112) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 2.2 [TaxId: 10090]}
evqlvesggdlvkpggslklscaasgfsfssygmswvrqtpdkrlewvatisngggytyy
pdsvkgrftisrdnakntlylqmsslksedsamyycarrerydengfaywgqgtlvtvs

SCOPe Domain Coordinates for d1hild1:

Click to download the PDB-style file with coordinates for d1hild1.
(The format of our PDB-style files is described here.)

Timeline for d1hild1: