SCOPe 2.02: Domain d3rv8d_: 3rv8 D:

Lineage for d3rv8d_ (3rv8 D:)

1. Root: SCOPe 2.02

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.161: ADC synthase [56321] (1 superfamily)
   duplication: contains four repeats of alpha-beta(2)-beta motif arranged in a 4 layer core structure: alpha/beta/beta/alpha; orthogonally packed beta-sheets

4. Superfamily d.161.1: ADC synthase [56322] (2 families)
   the active site is formed by additional structures inserted into the core structure

5. Family d.161.1.1: ADC synthase [56323] (6 proteins)

6. Protein automated matches [190419] (2 species)
   not a true protein

7. Species Mycobacterium tuberculosis [TaxId:1773] [195123] (5 PDB entries)

8. Domain d3rv8d_: 3rv8 D: [197437]
   automated match to d3logb_
   complexed with rvc, vce

Details for d3rv8d_

PDB Entry: 3rv8, 2.29 Å

PDB Description: Structure of a M. tuberculosis Salicylate Synthase, MbtI, in Complex with an Inhibitor with Cyclopropyl R-Group

PDB Compounds: (D:) Isochorismate synthase/isochorismate-pyruvate lyase mbtI

SCOPe Domain Sequences for d3rv8d_:

Sequence, based on SEQRES records:

>d3rv8d_ d.161.1.1 (D:) automated matches {Mycobacterium tuberculosis [TaxId: 1773]}
asssipmpagvnpadlaaelaavvtesvdedyllyecdgqwvlaagvqamveldsdelrv
irdgvtrrqqwsgrpgaalgeavdrllletdqafgwvafefgvhryglqqrlaphtplar
vfsprtrimvsekeirlfdagirhreaidrllatgvrevpqsrsvdvsddpsgfrrrvav
avdeiaagryhkvilsrcvevpfaidfpltyrlgrrhntpvrsfllqlggiralgyspel
vtavradgvviteplagtralgrgpaidrlarddlesnskeivehaisvrssleeitdia
epgsaavidfmtvrergsvqhlgstirarldpssdrmaalealfpavtasgipkaagvea
ifrldecprglysgavvmlsadggldaaltlraayqvggrtwlragagiieeseperefe
etceklstltpylvar

Sequence, based on observed residues (ATOM records):

>d3rv8d_ d.161.1.1 (D:) automated matches {Mycobacterium tuberculosis [TaxId: 1773]}
asssipmpagvnpadlaaelaavvtesvdedyllyecdgqwvlaagvqamveldsdelrv
irdgvtrrqqwsgrpgaalgeavdrllletdqafgwvafefgvhryglqqrlaphtplar
vfsprtrimvsekeirlfdagirhreaidrllatgvrevpqsrsvdvsddpsgfrrrvav
avdeiaagryhkvilsrcvevpfaidfpltyrlgrrhntpvrsfllqlggiralgyspel
vtavradgvviteplagtarddlesnskeivehaisvrssleeitdiaepgsaavidfmt
vreqhlgstirarldpssdrmaalealfpavtasgipkaagveaifrldecprglysgav
vmlsadggldaaltlraayqvggrtwlragagiieeseperefeetceklstltpylvar

Timeline for d3rv8d_:

• d3rv8d_ is new in SCOPe 2.02-stable
  
• d3rv8d_ appears in SCOPe 2.03
  
• d3rv8d_ appears in the current release, SCOPe 2.08