SCOPe 2.02: Domain d4hi3b_: 4hi3 B:

Lineage for d4hi3b_ (4hi3 B:)

1. Root: SCOPe 2.02

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.4: Viral cysteine protease of trypsin fold [50603] (4 proteins)

6. Protein Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) [74979] (6 species)
   contains an extra alpha-helical domain

7. Species SARS coronavirus [TaxId:227859] [89349] (57 PDB entries)

8. Domain d4hi3b_: 4hi3 B: [197388]
   automated match to d1z1ja_
   mutant

Details for d4hi3b_

PDB Entry: 4hi3, 2.09 Å

PDB Description: Crystal structure of dimeric R298A mutant of SARS coronavirus main protease

PDB Compounds: (B:) 3C-like proteinase

SCOPe Domain Sequences for d4hi3b_:

Sequence; same for both SEQRES and ATOM records:

>d4hi3b_ b.47.1.4 (B:) Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) {SARS coronavirus [TaxId: 227859]}
sgfrkmafpsgkvegcmvqvtcgtttlnglwlddtvycprhvictaedmlnpnyedllir
ksnhsflvqagnvqlrvighsmqncllrlkvdtsnpktpkykfvriqpgqtfsvlacyng
spsgvyqcamrpnhtikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdlegk
fygpfvdrqtaqaagtdttitlnvlawlyaavingdrwflnrftttlndfnlvamkynye
pltqdhvdilgplsaqtgiavldmcaalkellqngmngrtilgstiledeftpfdvvaqc
s

Timeline for d4hi3b_:

• d4hi3b_ is new in SCOPe 2.02-stable
  
• d4hi3b_ appears in SCOPe 2.03
  
• d4hi3b_ appears in the current release, SCOPe 2.08