SCOPe 2.02: Domain d4hiqb_: 4hiq B:

Lineage for d4hiqb_ (4hiq B:)

1. Root: SCOPe 2.02

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.3: Prealbumin-like [49451] (7 superfamilies)
   sandwich; 7 strands in 2 sheets, greek-key
   variations: some members have additional 1-2 strands to common fold

4. Superfamily b.3.4: Transthyretin (synonym: prealbumin) [49472] (2 families)

5. Family b.3.4.1: Transthyretin (synonym: prealbumin) [49473] (2 proteins)

6. Protein Transthyretin (synonym: prealbumin) [49474] (5 species)
   sandwich; 8 strands in 2 sheets

7. Species Human (Homo sapiens) [TaxId:9606] [49475] (150 PDB entries)
   Uniprot P02766 31-143

8. Domain d4hiqb_: 4hiq B: [197247]
   automated match to d1ttaa_
   complexed with 16v; mutant

Details for d4hiqb_

PDB Entry: 4hiq, 1.18 Å

PDB Description: The Structure of V122I Mutant Transthyretin in Complex with AG10

PDB Compounds: (B:) Transthyretin

SCOPe Domain Sequences for d4hiqb_:

Sequence; same for both SEQRES and ATOM records:

>d4hiqb_ b.3.4.1 (B:) Transthyretin (synonym: prealbumin) {Human (Homo sapiens) [TaxId: 9606]}
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysysttavitn

Timeline for d4hiqb_:

• d4hiqb_ is new in SCOPe 2.02-stable
  
• d4hiqb_ appears in SCOPe 2.03
  
• d4hiqb_ appears in the current release, SCOPe 2.08