Lineage for d4ek5a_ (4ek5 A:)

  1. Root: SCOPe 2.02
  2. 1190016Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 1220003Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1220004Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1220070Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1220363Protein Cyclin-dependent PK, CDK2 [88855] (2 species)
    CMGC group; CDKs subfamily; serine/threonine kinase
  7. 1220364Species Human (Homo sapiens) [TaxId:9606] [88856] (223 PDB entries)
    Uniprot P24941
  8. 1220376Domain d4ek5a_: 4ek5 A: [197164]
    automated match to d3ddqa_
    complexed with 03k

Details for d4ek5a_

PDB Entry: 4ek5 (more details), 1.6 Å

PDB Description: Crystal structure of the cdk2 in complex with aminopyrazole inhibitor
PDB Compounds: (A:) cyclin-dependent kinase 2

SCOPe Domain Sequences for d4ek5a_:

Sequence, based on SEQRES records: (download)

>d4ek5a_ d.144.1.7 (A:) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

Sequence, based on observed residues (ATOM records): (download)

>d4ek5a_ d.144.1.7 (A:) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkipstaireisllkelnhpnivklldv
ihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrdlk
pqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyystavdiwsl
gcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfs
kvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

SCOPe Domain Coordinates for d4ek5a_:

Click to download the PDB-style file with coordinates for d4ek5a_.
(The format of our PDB-style files is described here.)

Timeline for d4ek5a_: