SCOPe 2.04: Domain d4bfbb_: 4bfb B:

Lineage for d4bfbb_ (4bfb B:)

1. Root: SCOPe 2.04

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.0: automated matches [191552] (1 protein)
   not a true family

6. Protein automated matches [190954] (8 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [193159] (12 PDB entries)

8. Domain d4bfbb_: 4bfb B: [197147]
   Other proteins in same PDB: d4bfbd_, d4bfbe_
   automated match to d2qzka_
   complexed with b3p

Details for d4bfbb_

PDB Entry: 4bfb, 2.21 Å

PDB Description: bace2 xaperone complex

PDB Compounds: (B:) Beta-secretase 2

SCOPe Domain Sequences for d4bfbb_:

Sequence, based on SEQRES records:

>d4bfbb_ b.50.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
flamvdnlqgdsgrgyylemligtppqklqilvdtgssnfavagtphsyidtyfdterss
tyrskgfdvtvkytqgswtgfvgedlvtipkgfntsflvniatifesenfflpgikwngi
lglayatlakpsssletffdslvtqanipnvfsmqmcgaglpvagsgtnggslvlggiep
slykgdiwytpikeewyyqieilkleiggqslnldcreynadkaivdsgttllrlpqkvf
davveavaraslipefsdgfwtgsqlacwtnsetpwsyfpkisiylrdenssrsfritil
pqlyiqpmmgaglnyecyrfgispstnalvigatvmegfyvifdraqkrvgfaaspcaei
agaavseisgpfstedvasncvp

Sequence, based on observed residues (ATOM records):

>d4bfbb_ b.50.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
flamvdnlqgdsgrgyylemligtppqklqilvdtgssnfavagtphsyidtyfdterss
tyrskgfdvtvkytqgswtgfvgedlvtipkgfntsflvniatifesenfflpgikwngi
lglayatlakpsssletffdslvtqanipnvfsmqmcgaglpvaggslvlggiepslykg
diwytpikeewyyqieilkleiggqslnldcreynadkaivdsgttllrlpqkvfdavve
avaraslidgfwtgsqlacwtnsetpwsyfpkisiylrdenssrsfritilpqlyiqpmm
gaglnyecyrfgispstnalvigatvmegfyvifdraqkrvgfaaspcaeiagaavseis
gpfstedvasncvp

Timeline for d4bfbb_:

• d4bfbb_ first appeared in SCOPe 2.02
  
• d4bfbb_ appears in SCOPe 2.03
  
• d4bfbb_ appears in SCOPe 2.05
  
• d4bfbb_ appears in the current release, SCOPe 2.08