SCOPe 2.04: Domain d4bela_: 4bel A:

Lineage for d4bela_ (4bel A:)

1. Root: SCOPe 2.04

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.0: automated matches [191552] (1 protein)
   not a true family

6. Protein automated matches [190954] (8 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [193159] (12 PDB entries)

8. Domain d4bela_: 4bel A: [197144]
   Other proteins in same PDB: d4beld_, d4bele_
   automated match to d2qzka_
   complexed with b3p, cl

Details for d4bela_

PDB Entry: 4bel, 1.85 Å

PDB Description: bace2 xaperone complex

PDB Compounds: (A:) Beta-secretase 2

SCOPe Domain Sequences for d4bela_:

Sequence, based on SEQRES records:

>d4bela_ b.50.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
nflamvdnlqgdsgrgyylemligtppqklqilvdtgssnfavagtphsyidtyfdters
styrskgfdvtvkytqgswtgfvgedlvtipkgfntsflvniatifesenfflpgikwng
ilglayatlakpsssletffdslvtqanipnvfsmqmcgaglpvagsgtnggslvlggie
pslykgdiwytpikeewyyqieilkleiggqslnldcreynadkaivdsgttllrlpqkv
fdavveavaraslipefsdgfwtgsqlacwtnsetpwsyfpkisiylrdenssrsfriti
lpqlyiqpmmgaglnyecyrfgispstnalvigatvmegfyvifdraqkrvgfaaspcae
iagaavseisgpfstedvasncvp

Sequence, based on observed residues (ATOM records):

>d4bela_ b.50.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
nflamvdnlqgdsgrgyylemligtppqklqilvdtgssnfavagtphsyidtyfdters
styrskgfdvtvkytqgswtgfvgedlvtipkgfntsflvniatifesenfflpgikwng
ilglayatlakpsssletffdslvtqanipnvfsmqmcgagggslvlggiepslykgdiw
ytpikeewyyqieilkleiggqslnldcreynadkaivdsgttllrlpqkvfdavveava
rassdgfwtgsqlacwtpwsyfpkisiylrdenssrsfritilpqlyiqpmcyrfgisps
tnalvigatvmegfyvifdraqkrvgfaaspcaeiagaavseisgpfstedvasncvp

Timeline for d4bela_:

• d4bela_ first appeared in SCOPe 2.02
  
• d4bela_ appears in SCOPe 2.03
  
• d4bela_ appears in SCOPe 2.05
  
• d4bela_ appears in the current release, SCOPe 2.08