Lineage for d4hyha_ (4hyh A:)

  1. Root: SCOPe 2.03
  2. 1396887Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 1433536Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1433537Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1433619Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1433985Protein Cell cycle checkpoint kinase chk1 [64404] (1 species)
    CaMK group; CAMKL subfamily; serine/threonine kinase
  7. 1433986Species Human (Homo sapiens) [TaxId:9606] [64405] (70 PDB entries)
  8. 1433994Domain d4hyha_: 4hyh A: [196964]
    automated match to d2x8da_
    complexed with 1am

Details for d4hyha_

PDB Entry: 4hyh (more details), 1.7 Å

PDB Description: X-RAY Crystal structure of compound 39 bound to human chk1 kinase domain
PDB Compounds: (A:) Serine/threonine-protein kinase Chk1

SCOPe Domain Sequences for d4hyha_:

Sequence, based on SEQRES records: (download)

>d4hyha_ d.144.1.7 (A:) Cell cycle checkpoint kinase chk1 {Human (Homo sapiens) [TaxId: 9606]}
pfvedwdlvqtlgegaygevqlavnrvteeavavkivdmkravdcpenikkeicinkmln
henvvkfyghrregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvylhg
igithrdikpenlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellkrre
fhaepvdvwscgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsaplallh
kilvenpsaritipdikkdrwynkplkkg

Sequence, based on observed residues (ATOM records): (download)

>d4hyha_ d.144.1.7 (A:) Cell cycle checkpoint kinase chk1 {Human (Homo sapiens) [TaxId: 9606]}
pfvedwdlvqtlgegaygevqlavnrvteeavavkivdmkenikkeicinkmlnhenvvk
fyghrregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvylhgigithr
dikpenlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellkrrefhaepv
dvwscgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsaplallhkilven
psaritipdikkdrwynkplkkg

SCOPe Domain Coordinates for d4hyha_:

Click to download the PDB-style file with coordinates for d4hyha_.
(The format of our PDB-style files is described here.)

Timeline for d4hyha_: