SCOPe 2.08: Domain d4hi3a_: 4hi3 A:

Lineage for d4hi3a_ (4hi3 A:)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.4: Viral cysteine protease of trypsin fold [50603] (5 proteins)

6. Protein Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) [74979] (8 species)
   contains an extra alpha-helical domain

7. Species SARS coronavirus [TaxId:227859] [89349] (86 PDB entries)

8. Domain d4hi3a_: 4hi3 A: [196960]
   automated match to d1z1ja_
   mutant
   has additional subdomain(s) that are not in the common domain

Details for d4hi3a_

PDB Entry: 4hi3, 2.09 Å

PDB Description: Crystal structure of dimeric R298A mutant of SARS coronavirus main protease

PDB Compounds: (A:) 3C-like proteinase

SCOPe Domain Sequences for d4hi3a_:

Sequence; same for both SEQRES and ATOM records:

>d4hi3a_ b.47.1.4 (A:) Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) {SARS coronavirus [TaxId: 227859]}
sgfrkmafpsgkvegcmvqvtcgtttlnglwlddtvycprhvictaedmlnpnyedllir
ksnhsflvqagnvqlrvighsmqncllrlkvdtsnpktpkykfvriqpgqtfsvlacyng
spsgvyqcamrpnhtikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdlegk
fygpfvdrqtaqaagtdttitlnvlawlyaavingdrwflnrftttlndfnlvamkynye
pltqdhvdilgplsaqtgiavldmcaalkellqngmngrtilgstiledeftpfdvvaqc

Timeline for d4hi3a_:

• d4hi3a_ first appeared in SCOPe 2.02
  
• d4hi3a_ appears in SCOPe 2.07