Lineage for d4i77z_ (4i77 Z:)

  1. Root: SCOPe 2.04
  2. 1473060Class a: All alpha proteins [46456] (285 folds)
  3. 1486907Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 1486908Superfamily a.26.1: 4-helical cytokines [47266] (4 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 1486997Family a.26.1.2: Short-chain cytokines [47286] (14 proteins)
  6. 1487016Protein Interleukin-13 (IL-13) [63532] (1 species)
  7. 1487017Species Human (Homo sapiens) [TaxId:9606] [63533] (9 PDB entries)
  8. 1487018Domain d4i77z_: 4i77 Z: [196843]
    Other proteins in same PDB: d4i77l1, d4i77l2
    automated match to d1ik0a_

Details for d4i77z_

PDB Entry: 4i77 (more details), 1.9 Å

PDB Description: Lebrikizumab Fab bound to IL-13
PDB Compounds: (Z:) interleukin-13

SCOPe Domain Sequences for d4i77z_:

Sequence, based on SEQRES records: (download)

>d4i77z_ a.26.1.2 (Z:) Interleukin-13 (IL-13) {Human (Homo sapiens) [TaxId: 9606]}
talrelieelvnitqnqkaplcngsmvwsinltagmycaaleslinvsgcsaiektqrml
sgfcphkvsagqfsslhvrdtkievaqfvkdlllhlkklfr

Sequence, based on observed residues (ATOM records): (download)

>d4i77z_ a.26.1.2 (Z:) Interleukin-13 (IL-13) {Human (Homo sapiens) [TaxId: 9606]}
talrelieelvnitqplcngsmvwsinltagmycaaleslinvsgcsaiektqrmlsgfc
phkvsagqfsslhvrdtkievaqfvkdlllhlkklfr

SCOPe Domain Coordinates for d4i77z_:

Click to download the PDB-style file with coordinates for d4i77z_.
(The format of our PDB-style files is described here.)

Timeline for d4i77z_: