SCOPe 2.08: Domain d3zfec_: 3zfe C:

Lineage for d3zfec_ (3zfe C:)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.121: Nucleoplasmin-like/VP (viral coat and capsid proteins) [88632] (7 superfamilies)
   sandwich; 8 strands in 2 sheets; jelly-roll; some members can have additional 1-2 strands
   characteristic interaction between the domains of this fold allows the formation of five-fold and pseudo six-fold assemblies

4. Superfamily b.121.4: Positive stranded ssRNA viruses [88633] (10 families)

5. Family b.121.4.1: Picornaviridae-like VP (VP1, VP2, VP3 and VP4) [88634] (10 proteins)
   the order of the chains N-VP0-VP3-VP1-C is as in the polyprotein; VP0 is cleaved later upon capsid assembly to VP4 and VP2
   there is a different order in the shuffled genome of insect picorna-like proteins (Cricket paralysis virus)

6. Protein automated matches [190854] (27 species)
   not a true protein

7. Species Human enterovirus 71 [TaxId:39054] [195913] (16 PDB entries)

8. Domain d3zfec_: 3zfe C: [196803]
   Other proteins in same PDB: d3zfea_, d3zfeb_
   automated match to d1bev3_
   complexed with cl, na, sph

Details for d3zfec_

PDB Entry: 3zfe, 2.7 Å

PDB Description: Human enterovirus 71 in complex with capsid binding inhibitor WIN51711

PDB Compounds: (C:) vp3

SCOPe Domain Sequences for d3zfec_:

Sequence; same for both SEQRES and ATOM records:

>d3zfec_ b.121.4.1 (C:) automated matches {Human enterovirus 71 [TaxId: 39054]}
gfptepkpgtnqflttddgvsapilpnfhptpcihipgevrnllelcqvetilevnnvpt
natslmerlrfpvsaqagkgelcavfradpgrdgpwqstmlgqlcgyytqwsgslevtfm
ftgsfmatgkmliaytppggplpkdratamlgthviwdfglqssvtlvipwisnthyrah
ardgvfdyyttglvsiwyqtnyvvpigapntayiialaaaqknftmklckdtshilqtas
iq

Timeline for d3zfec_:

• d3zfec_ first appeared in SCOPe 2.02
  
• d3zfec_ appears in SCOPe 2.07