Lineage for d3s9dc_ (3s9d C:)

  1. Root: SCOPe 2.03
  2. 1253684Class a: All alpha proteins [46456] (284 folds)
  3. 1266371Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 1266372Superfamily a.26.1: 4-helical cytokines [47266] (4 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 1266633Family a.26.1.3: Interferons/interleukin-10 (IL-10) [47305] (9 proteins)
    contains an additional helix in one of the crossover connections
  6. 1266634Protein Interferon-alpha 2a [47314] (1 species)
  7. 1266635Species Human (Homo sapiens) [TaxId:9606] [47315] (3 PDB entries)
  8. 1266637Domain d3s9dc_: 3s9d C: [196189]
    Other proteins in same PDB: d3s9db1, d3s9db2, d3s9dd1, d3s9dd2
    automated match to d1itfa_
    complexed with cl

Details for d3s9dc_

PDB Entry: 3s9d (more details), 2 Å

PDB Description: binary complex between IFNa2 and IFNAR2
PDB Compounds: (C:) Interferon alpha-2

SCOPe Domain Sequences for d3s9dc_:

Sequence, based on SEQRES records: (download)

>d3s9dc_ a.26.1.3 (C:) Interferon-alpha 2a {Human (Homo sapiens) [TaxId: 9606]}
slgsrrtlmllaqmrrislfsclkdrhdfgfpqeefgnqfqkaetipvlaamiaqifnlf
stkdssaawdetlldkfytelyqqlndleacviqgvgvtetplmkedsilavrkyfqrit
lylkekkyspcawevvraeimrsfslst

Sequence, based on observed residues (ATOM records): (download)

>d3s9dc_ a.26.1.3 (C:) Interferon-alpha 2a {Human (Homo sapiens) [TaxId: 9606]}
slgsrrtlmllaqmrrislfsclkdrhdfgfpqpvlaamiaqifnlfstkdssaawdetl
ldkfytelyqqlndlealavrkyfqritlylkekkyspcawevvraeimrsfslst

SCOPe Domain Coordinates for d3s9dc_:

Click to download the PDB-style file with coordinates for d3s9dc_.
(The format of our PDB-style files is described here.)

Timeline for d3s9dc_: