Lineage for d3ux9a_ (3ux9 A:)

  1. Root: SCOPe 2.03
  2. 1253684Class a: All alpha proteins [46456] (284 folds)
  3. 1266371Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 1266372Superfamily a.26.1: 4-helical cytokines [47266] (4 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 1266633Family a.26.1.3: Interferons/interleukin-10 (IL-10) [47305] (9 proteins)
    contains an additional helix in one of the crossover connections
  6. 1266717Protein automated matches [190141] (2 species)
    not a true protein
  7. 1266718Species Human (Homo sapiens) [TaxId:9606] [187124] (4 PDB entries)
  8. 1266723Domain d3ux9a_: 3ux9 A: [195916]
    Other proteins in same PDB: d3ux9b1, d3ux9b2, d3ux9d1, d3ux9d2
    automated match to d1itfa_

Details for d3ux9a_

PDB Entry: 3ux9 (more details), 2.8 Å

PDB Description: Structural insights into a human anti-IFN antibody exerting therapeutic potential for systemic lupus erythematosus
PDB Compounds: (A:) Interferon alpha-1/13

SCOPe Domain Sequences for d3ux9a_:

Sequence, based on SEQRES records: (download)

>d3ux9a_ a.26.1.3 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}

Sequence, based on observed residues (ATOM records): (download)

>d3ux9a_ a.26.1.3 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d3ux9a_:

Click to download the PDB-style file with coordinates for d3ux9a_.
(The format of our PDB-style files is described here.)

Timeline for d3ux9a_: