SCOPe 2.02: Domain d4aexb_: 4aex B:

Lineage for d4aexb_ (4aex B:)

1. Root: SCOPe 2.02

2. Class e: Multi-domain proteins (alpha and beta) [56572] (66 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (6 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.4: RNA-dependent RNA-polymerase [56694] (3 proteins)

6. Protein automated matches [190260] (20 species)
   not a true protein

7. Species Hepatitis C virus [TaxId:11103] [187048] (31 PDB entries)

8. Domain d4aexb_: 4aex B: [195481]
   automated match to d3gnwb_
   complexed with po4

Details for d4aexb_

PDB Entry: 4aex, 2.41 Å

PDB Description: hcv-jfh1 ns5b polymerase structure at 2.4 angstrom in a primitive orthorhombic space group

PDB Compounds: (B:) RNA-directed RNA polymerase

SCOPe Domain Sequences for d4aexb_:

Sequence; same for both SEQRES and ATOM records:

>d4aexb_ e.8.1.4 (B:) automated matches {Hepatitis C virus [TaxId: 11103]}
smsyswtgalitpcspeeeklpinplsnsllryhnkvycttsksasqrakkvtfdrtqvl
dahydsvlkdiklaaskvsarlltleeacqltpphsarskygfgakevrslsgravnhik
svwkdlledpqtpipttimaknevfcvdpakggkkparlivypdlgvrvcekmalyditq
klpqavmgasygfqyspaqrveyllkawaekkdpmgfsydtrcfdstvterdirteesiy
qacslpeeartaihslterlyvggpmfnskgqtcgyrrcrasgvlttsmgntitcyvkal
aackaagivaptmlvcgddlvvisesqgteedernlrafteamtrysappgdpprpeydl
elitscssnvsvalgprgrrryyltrdpttplaraawetvrhspinswlgniiqyaptiw
vrmvlmthffsilmvqdtldqnlnfemygsvysvnpldlpaiierlhgldafsmhtyshh
eltrvasalrklgapplrvwksraravraslisrggkaavcgrylfnwavktklkltplp
earlldlsswftvgagggdifhsv

Timeline for d4aexb_:

• d4aexb_ is new in SCOPe 2.02-stable
  
• d4aexb_ appears in SCOPe 2.03
  
• d4aexb_ appears in the current release, SCOPe 2.08