SCOPe 2.07: Domain d4jr0a1: 4jr0 A:34-277

Lineage for d4jr0a1 (4jr0 A:34-277)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.17: Caspase-like [52128] (1 superfamily)
   3 layers, a/b/a; core: mixed beta-sheet of 6 strands, order 213456, strand 6 is antiparallel to the rest

4. Superfamily c.17.1: Caspase-like [52129] (3 families)
   mature protein may be composed of two chains folded in a single domain

5. Family c.17.1.1: Caspase catalytic domain [52130] (8 proteins)

6. Protein Apopain (caspase-3, cpp32) [52131] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52132] (28 PDB entries)

8. Domain d4jr0a1: 4jr0 A:34-277 [193127]
   Other proteins in same PDB: d4jr0a2, d4jr0b2
   automated match to d2j30a_
   complexed with cl

Details for d4jr0a1

PDB Entry: 4jr0, 1.8 Å

PDB Description: human procaspase-3 bound to ac-devd-cmk

PDB Compounds: (A:) Procaspase-3

SCOPe Domain Sequences for d4jr0a1:

Sequence, based on SEQRES records:

>d4jr0a1 c.17.1.1 (A:34-277) Apopain (caspase-3, cpp32) {Human (Homo sapiens) [TaxId: 9606]}
dnsykmdypemglciiinnknfhkstgmtsrsgtdvdaanlretfrnlkyevrnkndltr
eeivelmrdvskedhskrssfvcvllshgeegiifgtngpvdlkkitnffrgdrcrsltg
kpklfiiqacrgteldcgietasgvdddmachkipveadflyaystapgyyswrnskdgs
wfiqslcamlkqyadklefmhiltrvnrkvatefesfsfdatfhakkqipcivsmltkel
yfyh

Sequence, based on observed residues (ATOM records):

>d4jr0a1 c.17.1.1 (A:34-277) Apopain (caspase-3, cpp32) {Human (Homo sapiens) [TaxId: 9606]}
dnsykmdypemglciiinnknfhkstgmtsrsgtdvdaanlretfrnlkyevrnkndltr
eeivelmrdvskedhskrssfvcvllshgeegiifgtngpvdlkkitnffrgdrcrsltg
kpklfiiqacrgtkipveadflyaystapgyyswrnskdgswfiqslcamlkqyadklef
mhiltrvnrkvatefesfsfdatfhakkqipcivsmltkelyfyh

Timeline for d4jr0a1:

• d4jr0a1 first appeared in SCOPe 2.02, called d4jr0a_
  
• d4jr0a1 appears in SCOPe 2.06
  
• d4jr0a1 appears in the current release, SCOPe 2.08