SCOPe 2.03: Domain d2prga_: 2prg A:

Lineage for d2prga_ (2prg A:)

1. Root: SCOPe 2.03

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)
7. Species Human (Homo sapiens) [TaxId:9606] [48525] (82 PDB entries)
   Uniprot P37231 232-505

8. Domain d2prga_: 2prg A: [19311]
   Other proteins in same PDB: d2prgc_
   complexed with brl

Details for d2prga_

PDB Entry: 2prg, 2.3 Å

PDB Description: ligand-binding domain of the human peroxisome proliferator activated receptor gamma

PDB Compounds: (A:) Peroxisome proliferator activated receptor gamma

SCOPe Domain Sequences for d2prga_:

Sequence; same for both SEQRES and ATOM records:

>d2prga_ a.123.1.1 (A:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkh
itplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheii
ytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlai
fiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqiv
tehvqllqvikktetdmslhpllqeiykdly

Timeline for d2prga_:

• d2prga_ first appeared (with stable ids) in SCOP 1.55
  
• d2prga_ appears in SCOPe 2.02
  
• d2prga_ appears in SCOPe 2.04
  
• d2prga_ appears in the current release, SCOPe 2.08