SCOP 1.71: Domain d1eref_: 1ere F:

Lineage for d1eref_ (1ere F:)

1. Root: SCOP 1.71

2. Class a: All alpha proteins [46456] (226 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (1 family)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (32 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (19 PDB entries)

8. Domain d1eref_: 1ere F: [19305]
   complexed with est

Details for d1eref_

PDB Entry: 1ere, 3.1 Å

PDB Description: human estrogen receptor ligand-binding domain in complex with 17beta-estradiol

SCOP Domain Sequences for d1eref_:

Sequence, based on SEQRES records:

>d1eref_ a.123.1.1 (F:) Estrogen receptor alpha {Human (Homo sapiens)}
slalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrv
pgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmvei
fdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitd
tlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplydllleml
dahr

Sequence, based on observed residues (ATOM records):

>d1eref_ a.123.1.1 (F:) Estrogen receptor alpha {Human (Homo sapiens)}
slalsltadqmvsalldaeppilysefseasmmglltnladrelvhminwakrvpgfvdl
tlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveifdmlla
tssrfrmmnlqgeefvclksiillnsgvytftlksleekdhihrvldkitdtlihlmaka
gltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplydlllemldahr

Timeline for d1eref_:

• d1eref_ first appeared (with stable ids) in SCOP 1.55
  
• d1eref_ appears in SCOP 1.69
  
• d1eref_ appears in SCOP 1.73
  
• d1eref_ appears in the current release, SCOPe 2.08