SCOPe 2.06: Domain d1ereb_: 1ere B:

Lineage for d1ereb_ (1ere B:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (64 PDB entries)
   Uniprot P03372 307-551

8. Domain d1ereb_: 1ere B: [19301]
   complexed with est

Details for d1ereb_

PDB Entry: 1ere, 3.1 Å

PDB Description: human estrogen receptor ligand-binding domain in complex with 17beta-estradiol

PDB Compounds: (B:) Estrogen receptor

SCOPe Domain Sequences for d1ereb_:

Sequence, based on SEQRES records:

>d1ereb_ a.123.1.1 (B:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
slalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrv
pgfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmvei
fdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitd
tlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplydllleml
dahr

Sequence, based on observed residues (ATOM records):

>d1ereb_ a.123.1.1 (B:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
slalsltadqmvsalldaeppilysefseasmmglltnladrelvhminwakrvpgfvdl
tlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveifdmlla
tssrfrmmnlqgeefvclksiillnsgvytftlksleekdhihrvldkitdtlihlmaka
gltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplydlllemldahr

Timeline for d1ereb_:

• d1ereb_ first appeared (with stable ids) in SCOP 1.55
  
• d1ereb_ appears in SCOPe 2.05
  
• d1ereb_ appears in SCOPe 2.07
  
• d1ereb_ appears in the current release, SCOPe 2.08