SCOPe 2.02: Domain d4a4wa_: 4a4w A:

Lineage for d4a4wa_ (4a4w A:)

1. Root: SCOPe 2.02

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (12 species)
   not a true protein

7. Species Homo sapiens [TaxId:9606] [192490] (10 PDB entries)

8. Domain d4a4wa_: 4a4w A: [192809]
   automated match to d3ty0a_
   complexed with yfb

Details for d4a4wa_

PDB Entry: 4a4w, 2 Å

PDB Description: Ligand binding domain of human PPAR gamma in complex with amorfrutin B

PDB Compounds: (A:) Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d4a4wa_:

Sequence, based on SEQRES records:

>d4a4wa_ a.123.1.1 (A:) automated matches {Homo sapiens [TaxId: 9606]}
qlnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedki
kfkhitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygv
heiiytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnaleldds
dlaifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdl
rqivtehvqllqvikktetdmslhpllqeiykdly

Sequence, based on observed residues (ATOM records):

>d4a4wa_ a.123.1.1 (A:) automated matches {Homo sapiens [TaxId: 9606]}
qlnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedks
kevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslm
nkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviils
gdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllq
vikktetdmslhpllqeiykdly

Timeline for d4a4wa_:

• d4a4wa_ is new in SCOPe 2.02-stable
  
• d4a4wa_ appears in SCOPe 2.03
  
• d4a4wa_ appears in the current release, SCOPe 2.08