SCOPe 2.02: Domain d1fbya_: 1fby A:

Lineage for d1fbya_ (1fby A:)

1. Root: SCOPe 2.02

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Retinoid-X receptor alpha (RXR-alpha) [48510] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48511] (33 PDB entries)
   Uniprot P19793 227-458

8. Domain d1fbya_: 1fby A: [19275]
   complex with 9-cis retinoic acid
   complexed with rea

Details for d1fbya_

PDB Entry: 1fby, 2.25 Å

PDB Description: crystal structure of the human rxr alpha ligand binding domain bound to 9-cis retinoic acid

PDB Compounds: (A:) Retinoic acid receptor RXR-alpha

SCOPe Domain Sequences for d1fbya_:

Sequence, based on SEQRES records:

>d1fbya_ a.123.1.1 (A:) Retinoid-X receptor alpha (RXR-alpha) {Human (Homo sapiens) [TaxId: 9606]}
ssanedmpverileaelavepktetyveanmglnpsspndpvtnicqaadkqlftlvewa
kriphfselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahsagvg
aifdrvltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyasleay
ckhkypeqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemleap

Sequence, based on observed residues (ATOM records):

>d1fbya_ a.123.1.1 (A:) Retinoid-X receptor alpha (RXR-alpha) {Human (Homo sapiens) [TaxId: 9606]}
ssanedmpverileaelavepdpvtnicqaadkqlftlvewakriphfselplddqvill
ragwnelliasfshrsiavkdgillatglhvhrnsahsagvgaifdrvltelvskmrdmq
mdktelgclraivlfnpdskglsnpaevealrekvyasleayckhkypeqpgrfaklllr
lpalrsiglkclehlfffkligdtpidtflmemleap

Timeline for d1fbya_:

• d1fbya_ first appeared (with stable ids) in SCOP 1.55
  
• d1fbya_ appears in SCOPe 2.01
  
• d1fbya_ appears in SCOPe 2.03
  
• d1fbya_ appears in the current release, SCOPe 2.08