SCOPe 2.04: Domain d3rtsa_: 3rts A:

Lineage for d3rtsa_ (3rts A:)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.92: Zincin-like [55485] (2 superfamilies)
   contains mixed beta sheet with connection over free side of the sheet

4. Superfamily d.92.1: Metalloproteases ("zincins"), catalytic domain [55486] (18 families)

5. Family d.92.1.11: Matrix metalloproteases, catalytic domain [55528] (14 proteins)

6. Protein Macrophage elastase (MMP-12) [69780] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [69781] (36 PDB entries)
   Uniprot P39900 106-263 ! Uniprot P39900 106-264

8. Domain d3rtsa_: 3rts A: [191984]
   automated match to d1os9a_
   complexed with ca, klg, zn

Details for d3rtsa_

PDB Entry: 3rts, 1.81 Å

PDB Description: human mmp-12 catalytic domain in complex with*n*-hydroxy-2-(2- phenylethylsulfonamido)acetamide

PDB Compounds: (A:) Macrophage metalloelastase

SCOPe Domain Sequences for d3rtsa_:

Sequence; same for both SEQRES and ATOM records:

>d3rtsa_ d.92.1.11 (A:) Macrophage elastase (MMP-12) {Human (Homo sapiens) [TaxId: 9606]}
gpvwrkhyityrinnytpdmnredvdyairkafqvwsnvtplkfskintgmadilvvfar
gahgddhafdgkggilahafgpgsgiggdahfdedefwtthsggtnlfltavheighslg
lghssdpkavmfptykyvdintfrlsaddirgiqslyg

Timeline for d3rtsa_:

• d3rtsa_ first appeared in SCOPe 2.02
  
• d3rtsa_ appears in SCOPe 2.03
  
• d3rtsa_ appears in SCOPe 2.05
  
• d3rtsa_ appears in the current release, SCOPe 2.08