SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Protein: automated matches

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2078560Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2085156Superfamily c.1.10: Aldolase [51569] (9 families) (S)
    Common fold covers whole protein structure
  5. 2086424Family c.1.10.8: Class-II DAHP synthetase [141840] (2 protein domains)
    Pfam PF01474
  6. 2086439Protein automated matches [191084] (3 species)
    not a true protein

Species:

  1. 2086440Mycobacterium tuberculosis [TaxId:1773] [189668] (3 PDB entries)
    1. Domain for 2ypp:
    2. Domains for 3pfp:
      1. 2086442Domain d3pfpa1: 3pfp A:1-462 [183697]
        Other proteins in same PDB: d3pfpa2, d3pfpb2
        automated match to d2b7oa1
        complexed with 035, 036, cl, mn, so4
      2. 2086443Domain d3pfpb1: 3pfp B:1-462 [183698]
        Other proteins in same PDB: d3pfpa2, d3pfpb2
        automated match to d2b7oa1
        complexed with 035, 036, cl, mn, so4
    3. Domains for 5ckv:
      1. 2269472Domain d5ckva_: 5ckv A: [312778]
        automated match to d3kgfb_
        complexed with cl, gol, mn, phe, so4, trp, tyr
      2. 2269490Domain d5ckvb_: 5ckv B: [312796]
        automated match to d3kgfb_
        complexed with cl, gol, mn, phe, so4, trp, tyr
  2. 2086444Mycobacterium tuberculosis [TaxId:83332] [189029] (7 PDB entries)
    1. Domains for 2w19:
      1. 2086450Domain d2w19a_: 2w19 A: [169001]
        automated match to d2b7oa1
        complexed with gol, so4
      2. 2086451Domain d2w19b_: 2w19 B: [169002]
        automated match to d2b7oa1
        complexed with gol, so4
    2. Domains for 2w1a:
      1. 2086452Domain d2w1aa_: 2w1a A: [169003]
        automated match to d2b7oa1
        complexed with ce1, gol, mn, pg4, so4, tsa
      2. 2086453Domain d2w1ab_: 2w1a B: [169004]
        automated match to d2b7oa1
        complexed with ce1, gol, mn, pg4, so4, tsa
    3. Domains for 2ypo:
      1. 2086445Domain d2ypoa_: 2ypo A: [207711]
        automated match to d3rzib_
        complexed with gol, mn, phe, so4
      2. 2086446Domain d2ypob_: 2ypo B: [207712]
        automated match to d3rzib_
        complexed with gol, mn, phe, so4
    4. Domain for 2ypp:
    5. Domains for 2ypq:
      1. 2086454Domain d2ypqa_: 2ypq A: [207713]
        automated match to d3rzib_
        complexed with cl, gol, mn, po4, so4, trp, tyr
      2. 2086455Domain d2ypqb_: 2ypq B: [207714]
        automated match to d3rzib_
        complexed with cl, gol, mn, po4, so4, trp, tyr
    6. Domains for 3rzi:
      1. 2086447Domain d3rzia_: 3rzi A: [185227]
        automated match to d2b7oa1
        complexed with cl, gol, mn, phe, po4, so4, trp
      2. 2086448Domain d3rzib_: 3rzi B: [185228]
        automated match to d2b7oa1
        complexed with cl, gol, mn, phe, po4, so4, trp
    7. Domains for 5ckx:
      1. 2269502Domain d5ckxb_: 5ckx B: [312808]
        automated match to d3kgfb_
        complexed with cl, gol, mn, phe, so4, tsa, tyr
      2. 2269528Domain d5ckxa_: 5ckx A: [312833]
        automated match to d3kgfb_
        complexed with cl, gol, mn, phe, so4, tsa, tyr
  3. 2293859Corynebacterium glutamicum [TaxId:1718] [337160] (3 PDB entries)
    1. Domain for 5huc:
    2. Domains for 5hud:
      1. 2293863Domain d5hudc1: 5hud C:11-472 [337164]
        Other proteins in same PDB: d5hudc2, d5hudd2
        automated match to d3kgfb_
        complexed with gol, mn, peg, pg4, pge, po4, trp, tsa
      2. 2293887Domain d5huda_: 5hud A: [337188]
        Other proteins in same PDB: d5hudc2, d5hudd2
        automated match to d3kgfb_
        complexed with gol, mn, peg, pg4, pge, po4, trp, tsa
      3. 2293891Domain d5hudd1: 5hud D:11-472 [337192]
        Other proteins in same PDB: d5hudc2, d5hudd2
        automated match to d3kgfb_
        complexed with gol, mn, peg, pg4, pge, po4, trp, tsa
      4. 2293991Domain d5hudb_: 5hud B: [337292]
        Other proteins in same PDB: d5hudc2, d5hudd2
        automated match to d3kgfb_
        complexed with gol, mn, peg, pg4, pge, po4, trp, tsa
    3. Domain for 5hue:

More info for Protein automated matches from c.1.10.8: Class-II DAHP synthetase

Timeline for Protein automated matches from c.1.10.8: Class-II DAHP synthetase: