SCOP 1.71: Domain d1tx4a_: 1tx4 A:

Lineage for d1tx4a_ (1tx4 A:)

1. Root: SCOP 1.71

2. Class a: All alpha proteins [46456] (226 folds)

3. Fold a.116: GTPase activation domain, GAP [48349] (1 superfamily)
   multihelical

4. Superfamily a.116.1: GTPase activation domain, GAP [48350] (2 families)

5. Family a.116.1.1: BCR-homology GTPase activation domain (BH-domain) [48351] (5 proteins)
   Pfam 00620

6. Protein p50 RhoGAP domain [48352] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48353] (4 PDB entries)

8. Domain d1tx4a_: 1tx4 A: [19098]
   Other proteins in same PDB: d1tx4b_
   complexed with alf, gdp, mg

Details for d1tx4a_

PDB Entry: 1tx4, 1.65 Å

PDB Description: rho/rhogap/gdp(dot)alf4 complex

SCOP Domain Sequences for d1tx4a_:

Sequence; same for both SEQRES and ATOM records:

>d1tx4a_ a.116.1.1 (A:) p50 RhoGAP domain {Human (Homo sapiens)}
plpnqqfgvslqhlqeknpeqepipivlretvaylqahalttegifrrsantqvvrevqq
kynmglpvdfdqynalhlpavilktflrelpeplltfdlyphvvgflnidesqrvpatlq
vlqtlpeenyqvlrfltaflvqisahsdqnkmtntnlavvfgpnllwakdaaitlkainp
intftkflldhqgelf

Timeline for d1tx4a_:

• d1tx4a_ first appeared (with stable ids) in SCOP 1.55
  
• d1tx4a_ appears in SCOP 1.69
  
• d1tx4a_ appears in SCOP 1.73
  
• d1tx4a_ appears in the current release, SCOPe 2.08