SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Protein: automated matches

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2138632Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily)
    consists of two intertwined (sub)domains related by pseudo dyad; duplication
    3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest
  4. 2138633Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (6 families) (S)
    the constituent families form similar dimers
  5. 2138965Family c.77.1.0: automated matches [191423] (1 protein)
    not a true family
  6. 2138966Protein automated matches [190603] (16 species)
    not a true protein

Species:

  1. 2138967Aeropyrum pernix [TaxId:272557] [188121] (1 PDB entry)
  2. 2138970Aeropyrum pernix [TaxId:56636] [188025] (3 PDB entries)
    1. Domains for 1tyo:
      1. 2138971Domain d1tyoa_: 1tyo A: [161789]
        automated match to d1hqsa_
        complexed with enp
      2. 2138972Domain d1tyob_: 1tyo B: [161790]
        automated match to d1hqsa_
        complexed with enp
    2. Domains for 1v94:
      1. 2138973Domain d1v94a_: 1v94 A: [161837]
        automated match to d1hqsa_
      2. 2138974Domain d1v94b_: 1v94 B: [161838]
        automated match to d1hqsa_
    3. Domains for 1xgv:
      1. 2138975Domain d1xgva_: 1xgv A: [162074]
        automated match to d1hqsa_
      2. 2138976Domain d1xgvb_: 1xgv B: [162075]
        automated match to d1hqsa_
  3. 2138977Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [188333] (1 PDB entry)
  4. 2138994Burkholderia thailandensis [TaxId:271848] [269591] (1 PDB entry)
  5. 2138997Burkholderia xenovorans [TaxId:266265] [194800] (1 PDB entry)
  6. 2138999Clostridium thermocellum [TaxId:1515] [192994] (2 PDB entries)
    1. Domain for 4aou:
    2. Domains for 4aoy:
      1. 2139000Domain d4aoya_: 4aoy A: [192997]
        automated match to d2uxqa_
      2. 2139001Domain d4aoyb_: 4aoy B: [193001]
        automated match to d2uxqa_
      3. 2139002Domain d4aoyc_: 4aoy C: [192999]
        automated match to d2uxqa_
      4. 2139003Domain d4aoyd_: 4aoy D: [193004]
        automated match to d2uxqa_
  7. 2139005Desulfotalea psychrophila [TaxId:84980] [188344] (3 PDB entries)
    1. Domains for 2uxq:
      1. 2139006Domain d2uxqa_: 2uxq A: [168214]
        automated match to d1lwda_
        complexed with gol, mg, peg, so4
      2. 2139007Domain d2uxqb_: 2uxq B: [168215]
        automated match to d1lwda_
        complexed with gol, mg, peg, so4
      3. 2139008Domain d2uxqc_: 2uxq C: [168216]
        automated match to d1lwda_
        complexed with gol, mg, peg, so4
      4. 2139009Domain d2uxqd_: 2uxq D: [168217]
        automated match to d1lwda_
        complexed with gol, mg, peg, so4
    2. Domains for 2uxr:
      1. 2139011Domain d2uxra_: 2uxr A: [168218]
        automated match to d1lwda_
        complexed with gol, ict, mg
      2. 2139012Domain d2uxrb_: 2uxr B: [168219]
        automated match to d1lwda_
        complexed with gol, ict, mg
    3. Domain for 4aov:
  8. 2139013Pseudomonas putida [TaxId:303] [225791] (2 PDB entries)
    1. Domains for 3flk:
      1. 2139014Domain d3flka_: 3flk A: [210005]
        automated match to d3udua_
        complexed with dtt, mg, nai, nh4, oxl, so4
      2. 2139015Domain d3flkb_: 3flk B: [210006]
        automated match to d3udua_
        complexed with dtt, mg, nai, nh4, oxl, so4
      3. 2139016Domain d3flkc_: 3flk C: [210007]
        automated match to d3udua_
        complexed with dtt, mg, nai, nh4, oxl, so4
      4. 2139017Domain d3flkd_: 3flk D: [210008]
        automated match to d3udua_
        complexed with dtt, mg, nai, nh4, oxl, so4
    2. Domain for 3fmx:
  9. 2139019Salmonella typhimurium [TaxId:99287] [187811] (1 PDB entry)
  10. 2139022Schizosaccharomyces pombe [TaxId:284812] [189802] (2 PDB entries)
    1. Domains for 3ty3:
      1. 2139025Domain d3ty3a_: 3ty3 A: [186003]
        automated match to d1wpwa_
        complexed with ggg, gol
      2. 2139026Domain d3ty3b_: 3ty3 B: [186004]
        automated match to d1wpwa_
        complexed with ggg, gol
    2. Domains for 3ty4:
      1. 2139023Domain d3ty4a_: 3ty4 A: [186005]
        automated match to d1wpwa_
        complexed with gol
      2. 2139024Domain d3ty4b_: 3ty4 B: [186006]
        automated match to d1wpwa_
        complexed with gol
  11. 2139027Sulfolobus tokodaii [TaxId:273063] [187622] (3 PDB entries)
    1. Domains for 2dht:
      1. 2139032Domain d2dhta_: 2dht A: [163638]
        automated match to d1ai2a_
      2. 2139033Domain d2dhtb_: 2dht B: [163639]
        automated match to d1ai2a_
    2. Domains for 2e0c:
      1. 2139028Domain d2e0ca_: 2e0c A: [163781]
        automated match to d1ai2a_
      2. 2139029Domain d2e0cb_: 2e0c B: [163782]
        automated match to d1ai2a_
    3. Domains for 2e5m:
      1. 2139030Domain d2e5ma_: 2e5m A: [163834]
        automated match to d1ai2a_
        complexed with nap
      2. 2139031Domain d2e5mb_: 2e5m B: [163835]
        automated match to d1ai2a_
        complexed with nap
  12. 2139034Thermotoga maritima [TaxId:243274] [188199] (1 PDB entry)
  13. 2139037Thermus thermophilus [TaxId:262724] [189625] (2 PDB entries)
    1. Domains for 3ah3:
      1. 2139038Domain d3ah3a_: 3ah3 A: [172162]
        automated match to d1wpwa_
        complexed with edo, so4
      2. 2139039Domain d3ah3b_: 3ah3 B: [172163]
        automated match to d1wpwa_
        complexed with edo, so4
      3. 2139040Domain d3ah3c_: 3ah3 C: [172164]
        automated match to d1wpwa_
        complexed with edo, so4
      4. 2139041Domain d3ah3d_: 3ah3 D: [172165]
        automated match to d1wpwa_
        complexed with edo, so4
    2. Domains for 4yb4:
      1. 2268621Domain d4yb4c_: 4yb4 C: [311927]
        automated match to d1x0la_
        complexed with 48y, gol, mg, nai, so4
      2. 2268720Domain d4yb4d_: 4yb4 D: [312026]
        automated match to d1x0la_
        complexed with 48y, gol, mg, nai, so4
      3. 2268735Domain d4yb4b_: 4yb4 B: [312041]
        automated match to d1x0la_
        complexed with 48y, gol, mg, nai, so4
      4. 2268987Domain d4yb4a_: 4yb4 A: [312293]
        automated match to d1x0la_
        complexed with 48y, gol, mg, nai, so4
  14. 2139042Thermus thermophilus [TaxId:274] [188105] (1 PDB entry)
  15. 2283636Thermococcus kodakarensis [TaxId:69014] [326937] (4 PDB entries)
    1. Domain for 5hn3:
    2. Domain for 5hn4:
    3. Domain for 5hn5:
    4. Domain for 5hn6:
  16. 2286420Homo sapiens [TaxId:9606] [329721] (5 PDB entries)
    1. Domains for 5gre:
      1. 2286469Domain d5greb_: 5gre B: [329770]
        automated match to d3blxc_
        complexed with adp, cit, mg
      2. 2286496Domain d5grea_: 5gre A: [329797]
        automated match to d3blxo_
        complexed with adp, cit, mg
    2. Domains for 5grf:
      1. 2286428Domain d5grfb_: 5grf B: [329729]
        automated match to d3blxc_
        complexed with adp, cit, mg; mutant
      2. 2286510Domain d5grfa_: 5grf A: [329811]
        automated match to d3blxo_
        complexed with adp, cit, mg; mutant
    3. Domains for 5grh:
      1. 2286421Domain d5grha_: 5grh A: [329722]
        automated match to d3blxo_
        complexed with mg
      2. 2286475Domain d5grhb_: 5grh B: [329776]
        automated match to d3blxc_
        complexed with mg
    4. Domains for 5gri:
      1. 2286449Domain d5grib_: 5gri B: [329750]
        automated match to d3blxc_
        complexed with cit, mg
      2. 2286458Domain d5gria_: 5gri A: [329759]
        automated match to d3blxo_
        complexed with cit, mg
    5. Domains for 5grl:
      1. 2286477Domain d5grla_: 5grl A: [329778]
        automated match to d3blxo_
        complexed with adp, ict, mg
      2. 2286642Domain d5grlb_: 5grl B: [329943]
        automated match to d3blxc_
        complexed with adp, ict, mg

More info for Protein automated matches from c.77.1.0: automated matches

Timeline for Protein automated matches from c.77.1.0: automated matches: