Class c: Alpha and beta proteins (a/b) [51349] (148 folds) |
Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily) 3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest |
Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families) |
Family c.71.1.1: Dihydrofolate reductases [53598] (4 proteins) |
Protein automated matches [190514] (11 species) not a true protein |
Escherichia coli [TaxId:562] [187587] (3 PDB entries) |
Domain d2d0ka_: 2d0k A: [163534] automated match to d1ddra_ complexed with cl, fol; mutant |
Domain d2d0kb_: 2d0k B: [163535] automated match to d1ddra_ complexed with cl, fol; mutant |
Domain d4p66a_: 4p66 A: [258099] automated match to d3k74a_ complexed with ca, mtx, nap |
Domain d4p68a_: 4p68 A: [258098] automated match to d3k74a_ complexed with act, ca, mtx, nap |
Human (Homo sapiens) [TaxId:9606] [188894] (2 PDB entries) |
Domain d3n0ha_: 3n0h A: [181753] automated match to d1drfa_ complexed with so4, top; mutant |
Domain d3s3va_: 3s3v A: [185268] automated match to d1drfa_ complexed with so4, top; mutant |
Klebsiella pneumoniae [TaxId:1244085] [261371] (2 PDB entries) |
Domain d4or7a1: 4or7 A:1-159 [261372] Other proteins in same PDB: d4or7a2 automated match to d3k74a_ complexed with 25u, nap |
Domain d4osga_: 4osg A: [261862] automated match to d3k74a_ complexed with 06u, ca, cac, cl, eoh, nap, peg |
Domain d4osgb_: 4osg B: [261863] automated match to d3k74a_ complexed with 06u, ca, cac, cl, eoh, nap, peg |
Domain d4osgc_: 4osg C: [261866] automated match to d3k74a_ complexed with 06u, ca, cac, cl, eoh, nap, peg |
Domain d4osgd_: 4osg D: [261865] automated match to d3k74a_ complexed with 06u, ca, cac, cl, eoh, nap, peg |
Mycobacterium avium [TaxId:1764] [189124] (2 PDB entries) |
Domain d2w3va_: 2w3v A: [169047] automated match to d1df7a_ complexed with ndp, top |
Domain d2w3wa_: 2w3w A: [169048] automated match to d1df7a_ complexed with ndp, vg9 |
Mycobacterium tuberculosis [TaxId:1773] [327514] (2 PDB entries) |
Domain d5u26a1: 5u26 A:1-159 [327515] Other proteins in same PDB: d5u26a2 automated match to d1df7a_ complexed with edo, mmv, nap, so4 |
Domain d5u27a1: 5u27 A:1-159 [327526] Other proteins in same PDB: d5u27a2 automated match to d1df7a_ complexed with edo, nap, p65 |
Mycobacterium tuberculosis [TaxId:83332] [329359] (1 PDB entry) |
Domain d5ujfa1: 5ujf A:1-159 [329360] Other proteins in same PDB: d5ujfa2 automated match to d1df7a_ complexed with edo, mmv, so4 |
Plasmodium vivax [TaxId:5855] [187469] (4 PDB entries) |
Domain d2bl9a_: 2bl9 A: [163121] automated match to d1j3ia_ complexed with cp6, ndp |
Domain d2blaa_: 2bla A: [163122] automated match to d1j3ja_ complexed with cp6, mes, ndp; mutant |
Domain d2blba_: 2blb A: [241312] automated match to d2bl9a_ complexed with cp7, mes, ndp |
Domain d2blca_: 2blc A: [163123] automated match to d1j3ja_ complexed with cp7, mes, ndp; mutant |
Pneumocystis jirovecii [TaxId:42068] [197174] (1 PDB entry) |
Domain d4g8zx_: 4g8z X: [197175] automated match to d1dyra_ complexed with ndp, top; mutant |
Staphylococcus aureus [TaxId:1280] [195885] (5 PDB entries) |
Domain d3lg4a_: 3lg4 A: [247454] automated match to d4fgga_ complexed with 52v, ndp; mutant |
Domain d3lg4b_: 3lg4 B: [247455] automated match to d4fgga_ complexed with 52v, ndp; mutant |
Domain d3sgya_: 3sgy A: [200656] automated match to d3sgyb_ complexed with 06w, ndp |
Domain d3sgyb_: 3sgy B: [195886] automated match to d3fywx_ complexed with 06w, ndp |
Domain d3sh2a_: 3sh2 A: [249450] automated match to d3fywx_ complexed with 5dr, ndp |
Domain d3sh2b_: 3sh2 B: [249451] automated match to d3fywx_ complexed with 5dr, ndp |
Domain d4fgga1: 4fgg A:0-158 [196840] Other proteins in same PDB: d4fgga2 automated match to d3m08a_ complexed with 0u5, gol, nap |
Domain d4fgha1: 4fgh A:0-158 [196839] Other proteins in same PDB: d4fgha2 automated match to d3m08a_ complexed with 0u6, gol, nap |
Staphylococcus aureus [TaxId:273036] [274776] (1 PDB entry) |
Domain d4tu5x_: 4tu5 X: [274777] automated match to d3m08a_ complexed with 06w, ndp |
Yersinia pestis [TaxId:214092] [314715] (1 PDB entry) |
Domain d5hi6a1: 5hi6 A:1-160 [314716] Other proteins in same PDB: d5hi6a2, d5hi6b2 automated match to d3k74a_ complexed with ca, cl, k, mtx |
Domain d5hi6b1: 5hi6 B:1-160 [314723] Other proteins in same PDB: d5hi6a2, d5hi6b2 automated match to d3k74a_ |
Timeline for Protein automated matches from c.71.1.1: Dihydrofolate reductases: