SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Protein: automated matches

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1991436Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 1991437Superfamily a.26.1: 4-helical cytokines [47266] (4 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 1991528Family a.26.1.2: Short-chain cytokines [47286] (14 protein domains)
  6. 1991681Protein automated matches [190501] (4 species)
    not a true protein

Species:

  1. 1991682Human (Homo sapiens) [TaxId:9606] [187448] (15 PDB entries)
    1. Domain for 2b8x:
    2. Domain for 2b8y:
    3. Domain for 2b8z:
    4. Domain for 2b90:
    5. Domain for 2b91:
    6. Domain for 2d48:
    7. Domain for 2xqb:
    8. Domains for 3qt2:
      1. 1991704Domain d3qt2c_: 3qt2 C: [184613]
        automated match to d1hula_
        complexed with bgc, mpd
      2. 1991705Domain d3qt2d_: 3qt2 D: [184614]
        automated match to d1hula_
        complexed with bgc, mpd
      3. 1991706Domain d3qt2e_: 3qt2 E: [184615]
        automated match to d1hula_
        complexed with bgc, mpd
      4. 1991707Domain d3qt2f_: 3qt2 F: [184616]
        automated match to d1hula_
        complexed with bgc, mpd
    9. Domains for 3uf2:
      1. 1991690Domain d3uf2a_: 3uf2 A: [200970]
        automated match to d3uf2i_
      2. 1991691Domain d3uf2b_: 3uf2 B: [200971]
        automated match to d3uf2i_
      3. 1991692Domain d3uf2c_: 3uf2 C: [200972]
        automated match to d3uf2i_
      4. 1991693Domain d3uf2d_: 3uf2 D: [200973]
        automated match to d3uf2i_
      5. 1991694Domain d3uf2e_: 3uf2 E: [200974]
        automated match to d3uf2i_
      6. 1991695Domain d3uf2f_: 3uf2 F: [200975]
        automated match to d3uf2i_
      7. 1991696Domain d3uf2g_: 3uf2 G: [200976]
        automated match to d3uf2i_
      8. 1991697Domain d3uf2h_: 3uf2 H: [200977]
        automated match to d3uf2i_
      9. 1991698Domain d3uf2i_: 3uf2 I: [193558]
        automated match to d1hmca_
      10. 1991699Domain d3uf2j_: 3uf2 J: [200978]
        automated match to d3uf2i_
    10. Domains for 3va2:
      1. 1991708Domain d3va2a_: 3va2 A: [201212]
        automated match to d3va2b_
      2. 1991709Domain d3va2b_: 3va2 B: [193617]
        automated match to d3qt2c_
    11. Domains for 4fa8:
      1. 1991700Domain d4fa8e1: 4fa8 E:4-146 [193550]
        Other proteins in same PDB: d4fa8e2, d4fa8f2, d4fa8g2
        automated match to d1hmca_
        complexed with nag
      2. 1991701Domain d4fa8f1: 4fa8 F:4-147 [202023]
        Other proteins in same PDB: d4fa8e2, d4fa8f2, d4fa8g2
        automated match to d4fa8g_
        complexed with nag
      3. 1991702Domain d4fa8g1: 4fa8 G:4-148 [193551]
        Other proteins in same PDB: d4fa8e2, d4fa8f2, d4fa8g2
        automated match to d1hmca_
        complexed with nag
    12. Domain for 4nej:
    13. Domain for 4nem:
    14. Domains for 4wrl:
      1. 1991711Domain d4wrlb_: 4wrl B: [276040]
        automated match to d3uf5a_
        complexed with fuc, gal, nag, sia
      2. 1991712Domain d4wrld_: 4wrl D: [276043]
        automated match to d3uf5a_
        complexed with fuc, gal, nag, sia
    15. Domain for 5lqb:
  2. 1991713Mouse (Mus musculus) [TaxId:10090] [187941] (5 PDB entries)
    1. Domains for 2o26:
      1. 1991720Domain d2o26a1: 2o26 A:3-141 [166496]
        Other proteins in same PDB: d2o26a2
        automated match to d1exzb_
      2. 1991721Domain d2o26b_: 2o26 B: [166497]
        Other proteins in same PDB: d2o26a2
        automated match to d1exzb_
      3. 1991722Domain d2o26e_: 2o26 E: [166498]
        Other proteins in same PDB: d2o26a2
        automated match to d1exzb_
      4. 1991723Domain d2o26f_: 2o26 F: [166499]
        Other proteins in same PDB: d2o26a2
        automated match to d1exzb_
    2. Domains for 2o27:
      1. 1991714Domain d2o27a_: 2o27 A: [166500]
        automated match to d1exzb_
      2. 1991715Domain d2o27b_: 2o27 B: [166501]
        automated match to d1exzb_
    3. Domains for 3b5k:
      1. 1991724Domain d3b5ka_: 3b5k A: [172432]
        automated match to d1hula_
      2. 1991725Domain d3b5kb_: 3b5k B: [172433]
        automated match to d1hula_
    4. Domains for 3ejj:
      1. 1991718Domain d3ejja1: 3ejj A:4-148 [174984]
        Other proteins in same PDB: d3ejja2
        automated match to d1hmca_
      2. 1991719Domain d3ejjb_: 3ejj B: [174985]
        Other proteins in same PDB: d3ejja2
        automated match to d1hmca_
    5. Domains for 3uf5:
      1. 1991716Domain d3uf5a_: 3uf5 A: [194779]
        automated match to d3ejja_
        complexed with ca
      2. 1991717Domain d3uf5b_: 3uf5 B: [194778]
        automated match to d3ejja_
        complexed with ca
  3. 1991726Mustela putorius [TaxId:9669] [279075] (1 PDB entry)
  4. 2282881Ovis aries [TaxId:9940] [326182] (2 PDB entries)
    1. Domains for 5d22:
      1. 2282882Domain d5d22b_: 5d22 B: [326183]
        automated match to d4rs1a_
        complexed with act, edo
      2. 2282884Domain d5d22a_: 5d22 A: [326185]
        automated match to d4rs1a_
        complexed with act, edo
    2. Domains for 5d28:
      1. 2282883Domain d5d28b_: 5d28 B: [326184]
        automated match to d4rs1a_
        complexed with bma, man, nag, so4
      2. 2282920Domain d5d28c_: 5d28 C: [326221]
        automated match to d4rs1a_
        complexed with bma, man, nag, so4

More info for Protein automated matches from a.26.1.2: Short-chain cytokines

Timeline for Protein automated matches from a.26.1.2: Short-chain cytokines: