SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Protein: automated matches

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2190102Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
    contains large mixed beta-sheet
  4. 2190103Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (2 families) (S)
    automatically mapped to Pfam PF00303
  5. 2190104Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (4 protein domains)
  6. 2190399Protein automated matches [190469] (14 species)
    not a true protein

Species:

  1. 2190400Corynebacterium glutamicum [TaxId:196627] [227854] (2 PDB entries)
    1. Domains for 4h0r:
      1. 2190401Domain d4h0ra_: 4h0r A: [227855]
        automated match to d4knza_
      2. 2190402Domain d4h0rb_: 4h0r B: [234588]
        automated match to d4h0ra_
    2. Domains for 4h0u:
      1. 2190403Domain d4h0ua_: 4h0u A: [234590]
        automated match to d4h0ra_
        complexed with ump
      2. 2190404Domain d4h0ub_: 4h0u B: [234589]
        automated match to d4h0ra_
        complexed with ump
      3. 2190405Domain d4h0uc_: 4h0u C: [234599]
        automated match to d4h0ra_
        complexed with ump
      4. 2190406Domain d4h0ud_: 4h0u D: [227856]
        automated match to d4knza_
        complexed with ump
  2. 2190407Cryptosporidium hominis [TaxId:237895] [232024] (3 PDB entries)
    1. Domains for 2oip:
      1. 2190411Domain d2oipa2: 2oip A:181-521 [148785]
        Other proteins in same PDB: d2oipa1, d2oipb1, d2oipc1, d2oipd1, d2oipe1
        automated match to d1qzfa2
        complexed with cb3, mtx, ndp, ump; mutant
      2. 2190412Domain d2oipb2: 2oip B:181-521 [148787]
        Other proteins in same PDB: d2oipa1, d2oipb1, d2oipc1, d2oipd1, d2oipe1
        automated match to d1qzfa2
        complexed with cb3, mtx, ndp, ump; mutant
      3. 2190413Domain d2oipc2: 2oip C:186-521 [148789]
        Other proteins in same PDB: d2oipa1, d2oipb1, d2oipc1, d2oipd1, d2oipe1
        automated match to d1qzfa2
        complexed with cb3, mtx, ndp, ump; mutant
      4. 2190414Domain d2oipd2: 2oip D:181-521 [148791]
        Other proteins in same PDB: d2oipa1, d2oipb1, d2oipc1, d2oipd1, d2oipe1
        automated match to d1qzfa2
        complexed with cb3, mtx, ndp, ump; mutant
      5. 2190415Domain d2oipe2: 2oip E:181-521 [148793]
        Other proteins in same PDB: d2oipa1, d2oipb1, d2oipc1, d2oipd1, d2oipe1
        automated match to d1qzfa2
        complexed with cb3, mtx, ndp, ump; mutant
    2. Domains for 3dl5:
      1. 2190408Domain d3dl5b2: 3dl5 B:181-521 [232027]
        Other proteins in same PDB: d3dl5a1, d3dl5b1, d3dl5c1, d3dl5d1, d3dl5e1
        automated match to d1qzfa2
        complexed with cb3, dhf, ndp, ump; mutant
      2. 2190409Domain d3dl5c2: 3dl5 C:181-521 [232031]
        Other proteins in same PDB: d3dl5a1, d3dl5b1, d3dl5c1, d3dl5d1, d3dl5e1
        automated match to d1qzfa2
        complexed with cb3, dhf, ndp, ump; mutant
      3. 2190410Domain d3dl5d2: 3dl5 D:193-521 [232026]
        Other proteins in same PDB: d3dl5a1, d3dl5b1, d3dl5c1, d3dl5d1, d3dl5e1
        automated match to d1qzfa2
        complexed with cb3, dhf, ndp, ump; mutant
    3. Domains for 3hj3:
      1. 2190416Domain d3hj3a2: 3hj3 A:192-521 [232479]
        Other proteins in same PDB: d3hj3a1, d3hj3b1, d3hj3c1, d3hj3d1
        automated match to d1qzfa2
        complexed with cb3, mtx, ndp, ump; mutant
      2. 2190417Domain d3hj3b2: 3hj3 B:192-521 [236020]
        Other proteins in same PDB: d3hj3a1, d3hj3b1, d3hj3c1, d3hj3d1
        automated match to d3hj3a2
        complexed with cb3, mtx, ndp, ump; mutant
      3. 2190418Domain d3hj3c2: 3hj3 C:192-521 [236019]
        Other proteins in same PDB: d3hj3a1, d3hj3b1, d3hj3c1, d3hj3d1
        automated match to d3hj3a2
        complexed with cb3, mtx, ndp, ump; mutant
      4. 2190419Domain d3hj3d2: 3hj3 D:193-521 [236023]
        Other proteins in same PDB: d3hj3a1, d3hj3b1, d3hj3c1, d3hj3d1
        automated match to d3hj3a2
        complexed with cb3, mtx, ndp, ump; mutant
  3. 2190420Encephalitozoon cuniculi [TaxId:284813] [189107] (1 PDB entry)
  4. 2190422Enterococcus faecalis [TaxId:1351] [194752] (3 PDB entries)
    1. Domains for 3uwl:
      1. 2190423Domain d3uwla_: 3uwl A: [194756]
        automated match to d1tsla_
        complexed with edo, foz, so4
      2. 2190424Domain d3uwlb_: 3uwl B: [194753]
        automated match to d1tsla_
        complexed with edo, foz, so4
      3. 2190425Domain d3uwlc_: 3uwl C: [194754]
        automated match to d1tsla_
        complexed with edo, foz, so4
      4. 2190426Domain d3uwld_: 3uwl D: [194755]
        automated match to d1tsla_
        complexed with edo, foz, so4
    2. Domains for 4o7u:
      1. 2190427Domain d4o7ua_: 4o7u A: [268461]
        automated match to d3uwlb_
        complexed with edo, so4, ss7, thf
      2. 2190428Domain d4o7ub_: 4o7u B: [268460]
        automated match to d3uwlb_
        complexed with edo, so4, ss7, thf
      3. 2190429Domain d4o7uc_: 4o7u C: [268468]
        automated match to d3uwlb_
        complexed with edo, so4, ss7, thf
      4. 2190430Domain d4o7ud_: 4o7u D: [268470]
        automated match to d3uwlb_
        complexed with edo, so4, ss7, thf
    3. Domains for 5j7w:
      1. 2280052Domain d5j7wa_: 5j7w A: [323353]
        automated match to d3uwlb_
        complexed with mtx, so4
      2. 2280067Domain d5j7wd_: 5j7w D: [323368]
        automated match to d3uwlb_
        complexed with mtx, so4
      3. 2280073Domain d5j7wb_: 5j7w B: [323374]
        automated match to d3uwlb_
        complexed with mtx, so4
      4. 2280109Domain d5j7wc_: 5j7w C: [323410]
        automated match to d3uwlb_
        complexed with mtx, so4
  5. 2190431Fungus (Filobasidiella neoformans) [TaxId:5207] [187389] (1 PDB entry)
  6. 2190448Human (Homo sapiens) [TaxId:9606] [189245] (8 PDB entries)
    1. Domain for 3ed7:
    2. Domains for 3gg5:
      1. 2190463Domain d3gg5a_: 3gg5 A: [210523]
        automated match to d2aaza_
        complexed with po4, so4
      2. 2190464Domain d3gg5b_: 3gg5 B: [210524]
        automated match to d2aaza_
        complexed with po4, so4
      3. 2190465Domain d3gg5c_: 3gg5 C: [210525]
        automated match to d2aaza_
        complexed with po4, so4
      4. 2190466Domain d3gg5d_: 3gg5 D: [210526]
        automated match to d2aaza_
        complexed with po4, so4
    3. Domain for 3gh0:
    4. Domain for 3gh2:
    5. Domain for 4g2o:
    6. Domains for 4o1u:
      1. 2190452Domain d4o1ua_: 4o1u A: [268442]
        automated match to d4eb4a_
        complexed with cl, edo, so4; mutant
      2. 2190453Domain d4o1ub_: 4o1u B: [268435]
        automated match to d4eb4a_
        complexed with cl, edo, so4; mutant
    7. Domains for 4o1x:
      1. 2190454Domain d4o1xa_: 4o1x A: [268445]
        automated match to d4eb4a_
        complexed with cl, edo, so4; mutant
      2. 2190455Domain d4o1xb_: 4o1x B: [268447]
        automated match to d4eb4a_
        complexed with cl, edo, so4; mutant
      3. 2190456Domain d4o1xc_: 4o1x C: [268446]
        automated match to d4eb4a_
        complexed with cl, edo, so4; mutant
      4. 2190457Domain d4o1xd_: 4o1x D: [268448]
        automated match to d4eb4a_
        complexed with cl, edo, so4; mutant
    8. Domains for 4up1:
      1. 2190459Domain d4up1a_: 4up1 A: [274330]
        automated match to d4eb4a_
        complexed with so4
      2. 2190460Domain d4up1b_: 4up1 B: [274331]
        automated match to d4eb4a_
        complexed with so4
      3. 2190461Domain d4up1c_: 4up1 C: [274337]
        automated match to d4eb4a_
        complexed with so4
      4. 2190462Domain d4up1d_: 4up1 D: [274332]
        automated match to d4eb4a_
        complexed with so4
  7. 2190467Malaria parasite (Plasmodium falciparum) [TaxId:5833] [188759] (2 PDB entries)
    1. Domains for 3dg8:
      1. 2190468Domain d3dg8c_: 3dg8 C: [173918]
        Other proteins in same PDB: d3dg8a_, d3dg8b_
        automated match to d1j3ic_
        complexed with ndp, rj6, ump; mutant
      2. 2190469Domain d3dg8d_: 3dg8 D: [173919]
        Other proteins in same PDB: d3dg8a_, d3dg8b_
        automated match to d1j3ic_
        complexed with ndp, rj6, ump; mutant
    2. Domains for 3dga:
      1. 2190470Domain d3dgac_: 3dga C: [173920]
        Other proteins in same PDB: d3dgaa_, d3dgab_
        automated match to d1j3ic_
        complexed with ndp, rj1, ump
      2. 2190471Domain d3dgad_: 3dga D: [173921]
        Other proteins in same PDB: d3dgaa_, d3dgab_
        automated match to d1j3ic_
        complexed with ndp, rj1, ump
  8. 2190472Mouse (Mus musculus) [TaxId:10090] [225826] (7 PDB entries)
    1. Domains for 3ihh:
      1. 2190482Domain d3ihha_: 3ihh A: [305555]
        automated match to d4eb4a_
        complexed with ump
      2. 2190483Domain d3ihhb_: 3ihh B: [305556]
        automated match to d4eb4a_
        complexed with ump
      3. 2190484Domain d3ihhc_: 3ihh C: [305557]
        automated match to d4eb4a_
        complexed with ump
      4. 2190485Domain d3ihhd_: 3ihh D: [305558]
        automated match to d4eb4a_
        complexed with ump
      5. 2190486Domain d3ihhe_: 3ihh E: [305559]
        automated match to d4eb4a_
        complexed with ump
      6. 2190487Domain d3ihhf_: 3ihh F: [305560]
        automated match to d4eb4a_
        complexed with ump
    2. Domains for 3ihi:
      1. 2190488Domain d3ihia_: 3ihi A: [211690]
        automated match to d3ed7a_
        complexed with so4
      2. 2190489Domain d3ihib_: 3ihi B: [211691]
        automated match to d3ed7a_
        complexed with so4
    3. Domains for 4e5o:
      1. 2190476Domain d4e5oa_: 4e5o A: [220314]
        automated match to d3ed7a_
        complexed with bu1, ump
      2. 2190477Domain d4e5ob_: 4e5o B: [220315]
        automated match to d3ed7a_
        complexed with bu1, ump
      3. 2190478Domain d4e5oc_: 4e5o C: [220316]
        automated match to d3ed7a_
        complexed with bu1, ump
      4. 2190479Domain d4e5od_: 4e5o D: [220317]
        automated match to d3ed7a_
        complexed with bu1, ump
      5. 2190480Domain d4e5oe_: 4e5o E: [220318]
        automated match to d3ed7a_
        complexed with bu1, ump
      6. 2190481Domain d4e5of_: 4e5o F: [220319]
        automated match to d3ed7a_
        complexed with bu1, ump
    4. Domains for 4eb4:
      1. 2190490Domain d4eb4a_: 4eb4 A: [220395]
        automated match to d3ed7a_
        complexed with d16, dtt, gol, mes, so4, ump
      2. 2190491Domain d4eb4b_: 4eb4 B: [220396]
        automated match to d3ed7a_
        complexed with d16, dtt, gol, mes, so4, ump
      3. 2190492Domain d4eb4c_: 4eb4 C: [220397]
        automated match to d3ed7a_
        complexed with d16, dtt, gol, mes, so4, ump
      4. 2190493Domain d4eb4d_: 4eb4 D: [220398]
        automated match to d3ed7a_
        complexed with d16, dtt, gol, mes, so4, ump
    5. Domains for 4ein:
      1. 2190474Domain d4eina_: 4ein A: [220562]
        automated match to d3ed7a_
        complexed with gol, noh
      2. 2190475Domain d4einb_: 4ein B: [220563]
        automated match to d3ed7a_
        complexed with gol, noh
    6. Domain for 4ez8:
    7. Domains for 5fct:
      1. 2281096Domain d5fctb_: 5fct B: [324397]
        automated match to d4eb4a_
        complexed with c2f, ufp
      2. 2281120Domain d5fcta_: 5fct A: [324421]
        automated match to d4eb4a_
        complexed with c2f, ufp
  9. 2190494Mycobacterium tuberculosis [TaxId:1773] [189990] (2 PDB entries)
    1. Domains for 3qj7:
      1. 2190499Domain d3qj7a_: 3qj7 A: [184413]
        Other proteins in same PDB: d3qj7d2
        automated match to d1aiqa_
        complexed with spm, ump
      2. 2190500Domain d3qj7b_: 3qj7 B: [184414]
        Other proteins in same PDB: d3qj7d2
        automated match to d1aiqa_
        complexed with spm, ump
      3. 2190501Domain d3qj7c_: 3qj7 C: [184415]
        Other proteins in same PDB: d3qj7d2
        automated match to d1aiqa_
        complexed with spm, ump
      4. 2190502Domain d3qj7d1: 3qj7 D:1-263 [184416]
        Other proteins in same PDB: d3qj7d2
        automated match to d1aiqa_
        complexed with spm, ump
    2. Domains for 4foa:
      1. 2190495Domain d4foaa1: 4foa A:1-260 [221388]
        Other proteins in same PDB: d4foaa2
        automated match to d3qj7d_
        complexed with ufp
      2. 2190496Domain d4foab_: 4foa B: [221389]
        Other proteins in same PDB: d4foaa2
        automated match to d3qj7c_
        complexed with ufp
      3. 2190497Domain d4foac_: 4foa C: [221390]
        Other proteins in same PDB: d4foaa2
        automated match to d3qj7a_
        complexed with ufp
      4. 2190498Domain d4foad_: 4foa D: [221391]
        Other proteins in same PDB: d4foaa2
        automated match to d3qj7c_
        complexed with ufp
  10. 2190503Mycobacterium tuberculosis [TaxId:83332] [224938] (3 PDB entries)
    1. Domains for 4fog:
      1. 2190514Domain d4foga_: 4fog A: [221401]
        automated match to d1jg0a_
        complexed with c2f, ufp
      2. 2190515Domain d4fogb_: 4fog B: [221402]
        automated match to d1jg0a_
        complexed with c2f, ufp
      3. 2190516Domain d4fogc_: 4fog C: [221403]
        automated match to d1jg0a_
        complexed with c2f, ufp
      4. 2190517Domain d4fogd_: 4fog D: [221404]
        automated match to d1jg0a_
        complexed with c2f, ufp
    2. Domains for 4fox:
      1. 2190506Domain d4foxa_: 4fox A: [221413]
        automated match to d1jg0a_
        complexed with d16, ump
      2. 2190507Domain d4foxb_: 4fox B: [221414]
        automated match to d1jg0a_
        complexed with d16, ump
      3. 2190508Domain d4foxc_: 4fox C: [221415]
        automated match to d1jg0a_
        complexed with d16, ump
      4. 2190509Domain d4foxd_: 4fox D: [221416]
        automated match to d1jg0a_
        complexed with d16, ump
      5. 2190510Domain d4foxe_: 4fox E: [221417]
        automated match to d1jg0a_
        complexed with d16, ump
      6. 2190511Domain d4foxf_: 4fox F: [221418]
        automated match to d1jg0a_
        complexed with d16, ump
      7. 2190512Domain d4foxg_: 4fox G: [221419]
        automated match to d1jg0a_
        complexed with d16, ump
      8. 2190513Domain d4foxh_: 4fox H: [221420]
        automated match to d1jg0a_
        complexed with d16, ump
    3. Domains for 4fqs:
      1. 2190504Domain d4fqsa_: 4fqs A: [221464]
        automated match to d1jg0a_
        complexed with lya, ump
      2. 2190505Domain d4fqsb_: 4fqs B: [221465]
        automated match to d1jg0a_
        complexed with lya, ump
  11. 2190518Staphylococcus aureus [TaxId:158878] [195805] (1 PDB entry)
  12. 2190521Trichinella spiralis [TaxId:6334] [226731] (1 PDB entry)
  13. 2190526Varicella-zoster virus (strain oka vaccine) [TaxId:341980] [311478] (3 PDB entries)
    1. Domains for 4xsc:
      1. 2190527Domain d4xsca_: 4xsc A: [310053]
        automated match to d4ez8a_
        complexed with 1pe, bvp
      2. 2190528Domain d4xscb_: 4xsc B: [310054]
        automated match to d4ez8a_
        complexed with 1pe, bvp
      3. 2190529Domain d4xscc_: 4xsc C: [310055]
        automated match to d4ez8a_
        complexed with 1pe, bvp
      4. 2190530Domain d4xscd_: 4xsc D: [310056]
        automated match to d4ez8a_
        complexed with 1pe, bvp
    2. Domains for 4xsd:
      1. 2190531Domain d4xsda_: 4xsd A: [310057]
        automated match to d4ez8a_
        complexed with ump
      2. 2190532Domain d4xsdb_: 4xsd B: [310058]
        automated match to d4ez8a_
        complexed with ump
      3. 2190533Domain d4xsdc_: 4xsd C: [310059]
        automated match to d4ez8a_
        complexed with ump
      4. 2190534Domain d4xsdd_: 4xsd D: [310060]
        automated match to d4ez8a_
        complexed with ump
    3. Domains for 4xse:
      1. 2190535Domain d4xsea_: 4xse A: [310061]
        automated match to d4ez8a_
        complexed with po4
      2. 2190536Domain d4xseb_: 4xse B: [310062]
        automated match to d4ez8a_
        complexed with po4
      3. 2190537Domain d4xsec_: 4xse C: [310063]
        automated match to d4ez8a_
        complexed with po4
      4. 2190538Domain d4xsed_: 4xse D: [310064]
        automated match to d4ez8a_
        complexed with po4
  14. 2285170Human herpesvirus 8 [TaxId:37296] [328471] (3 PDB entries)
    1. Domains for 5h38:
      1. 2285230Domain d5h38a_: 5h38 A: [328531]
        automated match to d1hvya_
        complexed with po4
      2. 2285340Domain d5h38b_: 5h38 B: [328641]
        automated match to d1hvya_
        complexed with po4
    2. Domains for 5h39:
      1. 2285171Domain d5h39a_: 5h39 A: [328472]
        automated match to d1hvya_
        complexed with ump
      2. 2285229Domain d5h39b_: 5h39 B: [328530]
        automated match to d1hvya_
        complexed with ump
    3. Domains for 5h3a:
      1. 2285192Domain d5h3ab_: 5h3a B: [328493]
        automated match to d1hvya_
        complexed with d16, ump
      2. 2285323Domain d5h3aa_: 5h3a A: [328624]
        automated match to d1hvya_
        complexed with d16, ump

More info for Protein automated matches from d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase

Timeline for Protein automated matches from d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase: