SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Protein: automated matches

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2078560Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2085156Superfamily c.1.10: Aldolase [51569] (9 families) (S)
    Common fold covers whole protein structure
  5. 2086002Family c.1.10.3: 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) [51594] (2 protein domains)
    hybrid of classes I and II aldolase
    automatically mapped to Pfam PF00490
  6. 2086040Protein automated matches [190088] (5 species)
    not a true protein

Species:

  1. 2086041Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [186810] (1 PDB entry)
  2. 2086043Pseudomonas aeruginosa [TaxId:287] [187506] (8 PDB entries)
    1. Domains for 1w54:
      1. 2086055Domain d1w54a_: 1w54 A: [161891]
        automated match to d1gzgb_
        complexed with fmt, k, mg, zn; mutant
      2. 2086056Domain d1w54b_: 1w54 B: [161892]
        automated match to d1gzgb_
        complexed with fmt, k, mg, zn; mutant
    2. Domains for 2c13:
      1. 2086053Domain d2c13a_: 2c13 A: [163211]
        automated match to d1gzgb_
        complexed with cl, k, mg, peg, pge
      2. 2086054Domain d2c13b_: 2c13 B: [163212]
        automated match to d1gzgb_
        complexed with cl, k, mg, peg, pge
    3. Domains for 2c14:
      1. 2086049Domain d2c14a_: 2c14 A: [163213]
        automated match to d1gzgb_
        complexed with mg
      2. 2086050Domain d2c14b_: 2c14 B: [163214]
        automated match to d1gzgb_
        complexed with mg
    4. Domains for 2c15:
      1. 2086044Domain d2c15a_: 2c15 A: [163215]
        automated match to d1gzgb_
        complexed with mg
      2. 2086045Domain d2c15b_: 2c15 B: [163216]
        automated match to d1gzgb_
        complexed with mg
    5. Domains for 2c16:
      1. 2086057Domain d2c16a_: 2c16 A: [163217]
        automated match to d1gzgb_
        complexed with cl, mg, peg, pge
      2. 2086058Domain d2c16b_: 2c16 B: [163218]
        automated match to d1gzgb_
        complexed with cl, mg, peg, pge
    6. Domains for 2c18:
      1. 2086047Domain d2c18a_: 2c18 A: [163219]
        automated match to d1gzgb_
        complexed with cl, mg, na, pge
      2. 2086048Domain d2c18b_: 2c18 B: [163220]
        automated match to d1gzgb_
        complexed with cl, mg, na, pge
    7. Domains for 2c19:
      1. 2086051Domain d2c19a_: 2c19 A: [163221]
        automated match to d1gzgb_
        complexed with mg, na
      2. 2086052Domain d2c19b_: 2c19 B: [163222]
        automated match to d1gzgb_
        complexed with mg, na
    8. Domain for 2woq:
  3. 2086059Pseudomonas aeruginosa, PA01 [TaxId:208964] [188066] (6 PDB entries)
    1. Domains for 1w56:
      1. 2086068Domain d1w56a_: 1w56 A: [161893]
        automated match to d1gzgb_
        complexed with fmt, k, mg, zn; mutant
      2. 2086069Domain d1w56b_: 1w56 B: [161894]
        automated match to d1gzgb_
        complexed with fmt, k, mg, zn; mutant
    2. Domains for 1w5m:
      1. 2086062Domain d1w5ma_: 1w5m A: [161895]
        automated match to d1gzgb_
        complexed with cl, fmt, mg, zn; mutant
      2. 2086063Domain d1w5mb_: 1w5m B: [161896]
        automated match to d1gzgb_
        complexed with cl, fmt, mg, zn; mutant
    3. Domains for 1w5n:
      1. 2086066Domain d1w5na_: 1w5n A: [161897]
        automated match to d1gzgb_
        complexed with cl, fmt, mg, na, zn; mutant
      2. 2086067Domain d1w5nb_: 1w5n B: [161898]
        automated match to d1gzgb_
        complexed with cl, fmt, mg, na, zn; mutant
    4. Domains for 1w5o:
      1. 2086070Domain d1w5oa_: 1w5o A: [161899]
        automated match to d1gzgb_
        complexed with gol, k, mg, zn; mutant
      2. 2086071Domain d1w5ob_: 1w5o B: [161900]
        automated match to d1gzgb_
        complexed with gol, k, mg, zn; mutant
    5. Domains for 1w5p:
      1. 2086064Domain d1w5pa_: 1w5p A: [161901]
        automated match to d1gzgb_
        complexed with edo, fmt, gol, k, mg, so4, zn; mutant
      2. 2086065Domain d1w5pb_: 1w5p B: [161902]
        automated match to d1gzgb_
        complexed with edo, fmt, gol, k, mg, so4, zn; mutant
    6. Domains for 1w5q:
      1. 2086060Domain d1w5qa_: 1w5q A: [161903]
        automated match to d1gzgb_
        complexed with fmt, mg, na, zn; mutant
      2. 2086061Domain d1w5qb_: 1w5q B: [161904]
        automated match to d1gzgb_
        complexed with fmt, mg, na, zn; mutant
  4. 2271765Escherichia coli [TaxId:83333] [315066] (1 PDB entry)
  5. 2283730Escherichia coli [TaxId:562] [327031] (1 PDB entry)

More info for Protein automated matches from c.1.10.3: 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase)

Timeline for Protein automated matches from c.1.10.3: 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase):

  • Protein automated matches from c.1.10.3: 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) first appeared in SCOPe 2.01
  • Protein automated matches from c.1.10.3: 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) appears in SCOPe 2.05