SCOP 1.75: Domain d4coxb1: 4cox B:74-583

Lineage for d4coxb1 (4cox B:74-583)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.93: Heme-dependent peroxidases [48112] (1 superfamily)
   multihelical; consists of two all-alpha domains

4. Superfamily a.93.1: Heme-dependent peroxidases [48113] (3 families)

5. Family a.93.1.2: Myeloperoxidase-like [48132] (2 proteins)

6. Protein Prostaglandin H2 synthase [48136] (2 species)
   contains EGF-like module

7. Species Mouse (Mus musculus) [TaxId:10090] [48138] (8 PDB entries)

8. Domain d4coxb1: 4cox B:74-583 [18723]
   Other proteins in same PDB: d4coxa2, d4coxb2, d4coxc2, d4coxd2

Details for d4coxb1

PDB Entry: 4cox, 2.9 Å

PDB Description: cyclooxygenase-2 (prostaglandin synthase-2) complexed with a non- selective inhibitor, indomethacin

PDB Compounds: (B:) cyclooxygenase-2

SCOP Domain Sequences for d4coxb1:

Sequence; same for both SEQRES and ATOM records:

>d4coxb1 a.93.1.2 (B:74-583) Prostaglandin H2 synthase {Mouse (Mus musculus) [TaxId: 10090]}
fltriklllkptpntvhyilthfkgvwnivnnipflrslimkyvltsrsylidspptynv
hygyksweafsnlsyytralppvaddcptpmgvkgnkelpdskevlekvllrrefipdpq
gsnmmfaffaqhfthqffktdhkrgpgftrglghgvdlnhiygetldrqhklrlfkdgkl
kyqviggevypptvkdtqvemiypphipenlqfavgqevfglvpglmmyatiwlrehqrv
cdilkqehpewgdeqlfqtskliligetikiviedyvqhlsgyhfklkfdpellfnqqfq
yqnriasefntlyhwhpllpdtfniedqeysfkqflynnsillehgltqfvesftrqiag
rvaggrnvpiavqavakasidqsremkyqslneyrkrfslkpytsfeeltgekemaaelk
alysdidvmelypallvekprpdaifgetmvelgapfslkglmgnpicspqywkpstfgg
evgfkiintasiqslicnnvkgcpftsfnvq

Timeline for d4coxb1:

• d4coxb1 first appeared (with stable ids) in SCOP 1.55
  
• d4coxb1 appears in SCOP 1.73
  
• d4coxb1 appears in SCOPe 2.01
  
• d4coxb1 appears in the current release, SCOPe 2.08