SCOPe 2.08: Domain d3udld_: 3udl D:

Lineage for d3udld_ (3udl D:)

1. Root: SCOPe 2.08

2. Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (9 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.4: RNA-dependent RNA-polymerase [56694] (3 proteins)

6. Protein automated matches [190260] (25 species)
   not a true protein

7. Species Hepatitis C virus subtype 1b [TaxId:31647] [187148] (6 PDB entries)

8. Domain d3udld_: 3udl D: [186237]
   automated match to d1nb4a_
   complexed with kli

Details for d3udld_

PDB Entry: 3udl, 2.17 Å

PDB Description: 3-heterocyclyl quinolone bound to HCV NS5B

PDB Compounds: (D:) hcv ns5b polymerase

SCOPe Domain Sequences for d3udld_:

Sequence, based on SEQRES records:

>d3udld_ e.8.1.4 (D:) automated matches {Hepatitis C virus subtype 1b [TaxId: 31647]}
smsytwtgalitpcaaeesklpinalsnsllrhhnmvyattsrsaglrqkkvtfdrlqvl
ddhyrdvlkemkakastvkakllsveeackltpphsakskfgygakdvrnlsskavnhih
svwkdlledtvtpidttimaknevfcvqpekggrkparlivfpdlgvrvcekmalydvvs
tlpqvvmgssygfqyspgqrveflvntwkskknpmgfsydtrcfdstvtendirveesiy
qccdlapearqaikslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylkas
aacraaklqdctmlvngddlvvicesagtqedaaslrvfteamtrysappgdppqpeydl
elitscssnvsvahdasgkrvyyltrdpttplaraawetarhtpvnswlgniimyaptlw
armilmthffsillaqeqlekaldcqiygacysiepldlpqiierlhglsafslhsyspg
einrvasclrklgvpplrvwrhrarsvrarllsqggraatcgkylfnwavktklkltpip
aasqldlsgwfvagysggdiyhs

Sequence, based on observed residues (ATOM records):

>d3udld_ e.8.1.4 (D:) automated matches {Hepatitis C virus subtype 1b [TaxId: 31647]}
smsytwtgalitpcaaeesklplsnsllrhhnmvyattsrsaglrqkkvtfdrlqvlddh
yrdvlkemkakastvkakllsveeackltpphsakskfgygakdvrnlsskavnhihsvw
kdlledtvtpidttimaknevfcvqrkparlivfpdlgvrvcekmalydvvstlpqvvmg
ssygfqyspgqrveflvntwkskknpmgfsydtrcfdstvtendirveesiyqccdlape
arqaikslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylkasaacraakl
qdctmlvngddlvvicesagtqedaaslrvfteamtrysappgdppqpeydlelitscss
nvsvahdasgkrvyyltrdpttplaraawetarhtpvnswlgniimyaptlwarmilmth
ffsillaqeqlekaldcqiygacysiepldlpqiierlhglsafslhsyspgeinrvasc
lrklgvpplrvwrhrarsvrarllsqggraatcgkylfnwavktklkltpipaasqldls
gwfvagysggdiyhs

Timeline for d3udld_:

• d3udld_ first appeared in SCOPe 2.01
  
• d3udld_ appears in SCOPe 2.07