SCOPe 2.05: Domain d3tamb_: 3tam B:

Lineage for d3tamb_ (3tam B:)

1. Root: SCOPe 2.05

2. Class e: Multi-domain proteins (alpha and beta) [56572] (68 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (7 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.2: Reverse transcriptase [56686] (3 proteins)

6. Protein automated matches [190211] (5 species)
   not a true protein

7. Species Hiv-1 m:b_hxb2r [TaxId:11706] [187165] (10 PDB entries)

8. Domain d3tamb_: 3tam B: [185741]
   Other proteins in same PDB: d3tama2
   automated match to d1c1cb_
   complexed with m06; mutant

Details for d3tamb_

PDB Entry: 3tam, 2.51 Å

PDB Description: Crystal structure of HIV-1 reverse transcriptase (K103N mutant) in complex with inhibitor M06

PDB Compounds: (B:) p51 RT

SCOPe Domain Sequences for d3tamb_:

Sequence, based on SEQRES records:

>d3tamb_ e.8.1.2 (B:) automated matches {Hiv-1 m:b_hxb2r [TaxId: 11706]}
ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaik
kkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkknksvtvldvgdayfsvpldedf
rkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqym
ddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpi
vlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeaelela
enreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtnd
vkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvk
lwyq

Sequence, based on observed residues (ATOM records):

>d3tamb_ e.8.1.2 (B:) automated matches {Hiv-1 m:b_hxb2r [TaxId: 11706]}
ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaik
kstkwrklvdfrelnkrtqdfwevqlgiphpaglkknksvtvldvgdayfsvpldedfrk
ytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymdd
lyvgsdleigqhrtkieelrqhllrwgltgyelhpdkwtvqpivlpekdswtvndiqklv
gklnwasqiypgikvrqlckllrgtkalteviplteeaelelaenreilkepvhgvyydp
skdliaeiqkqgqgqwtyqiyqepfknlktgkyarhtndvkqlteavqkittesiviwgk
tpkfklpiqketwetwwteywqatwipewefvntpplvklwyq

Timeline for d3tamb_:

• d3tamb_ first appeared in SCOPe 2.01
  
• d3tamb_ appears in SCOPe 2.04
  
• d3tamb_ appears in SCOPe 2.06
  
• d3tamb_ appears in the current release, SCOPe 2.08