SCOPe 2.01: Domain d3q4za_: 3q4z A:

Lineage for d3q4za_ (3q4z A:)

1. Root: SCOPe 2.01

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein pak1 [56146] (1 species)
   OPK group; PAK/STE20 subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [56147] (9 PDB entries)

8. Domain d3q4za_: 3q4z A: [184214]
   automated match to d1f3mc_
   complexed with anp, mg

Details for d3q4za_

PDB Entry: 3q4z, 1.89 Å

PDB Description: Structure of unphosphorylated PAK1 kinase domain

PDB Compounds: (A:) Serine/threonine-protein kinase PAK 1

SCOPe Domain Sequences for d3q4za_:

Sequence, based on SEQRES records:

>d3q4za_ d.144.1.7 (A:) pak1 {Human (Homo sapiens) [TaxId: 9606]}
eeileklriivsvgdpkkkytrfekigqgasgtvytamdvatgqevairqmnlqqqpkke
liineilvmrenknpnivnyldsylvgdelwvvmeylaggsltdvvtetcmdegqiaavc
reclqaleflhsnqvihrniksdnillgmdgsvkltdfgfcaqitpeqskrstmvgtpyw
mapevvtrkaygpkvdiwslgimaiemiegeppylnenplralyliatngtpelqnpekl
saifrdflnrclemdvekrgsakeliqhqflkiakplssltpliaaakeatknnhl

Sequence, based on observed residues (ATOM records):

>d3q4za_ d.144.1.7 (A:) pak1 {Human (Homo sapiens) [TaxId: 9606]}
eeileklriivsvgdpkfekigqgasgtvytamdqevairqmnlkeliineilvmrenkn
pnivnyldsylvgdelwvvmeylaggsltdvvtetcmdegqiaavcreclqaleflhsnq
vihrniksdnillgmdgsvkltdfgfcaqitpeqskrstmvgtpywmapevvtrkaygpk
vdiwslgimaiemiegeppylnenplralyliatngtpelqnpeklsaifrdflnrclem
dvekrgsakeliqhqflkiakplssltpliaaakeatknnhl

Timeline for d3q4za_:

• d3q4za_ is new in SCOPe 2.01-stable
  
• d3q4za_ appears in SCOPe 2.02
  
• d3q4za_ appears in the current release, SCOPe 2.08, called d3q4za1