SCOPe 2.06: Domain d3pzea_: 3pze A:

Lineage for d3pzea_ (3pze A:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (17 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (653 PDB entries)

8. Domain d3pzea_: 3pze A: [184091]
   automated match to d1jnka_
   complexed with cfk, so4

Details for d3pzea_

PDB Entry: 3pze, 2 Å

PDB Description: jnk1 in complex with inhibitor

PDB Compounds: (A:) Mitogen-activated protein kinase 8

SCOPe Domain Sequences for d3pzea_:

Sequence, based on SEQRES records:

>d3pzea_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dnnfysveigdstftvlkryqnlkpigsgaqgivcaaydailernvaikklsrpfqnqth
akrayrelvlmkcvnhkniigllnvftpqksleefqdvyivmelmdanlcqviqmeldhe
rmsyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglartagtsfmmtpyv
vtryyrapevilgmgykenvdlwsvgcimgemvchkilfpgrdyidqwnkvieqlgtpcp
efmkklqptvrtyvenrpkyagysfeklfpdvlfpadsehnklkasqardllskmlvida
skrisvdealqhpyinvwydpseaeapppkipdkqlderehtieewkeliykevmd

Sequence, based on observed residues (ATOM records):

>d3pzea_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dnnfysveigdstftvlkryqnlkpigsgaqgivcaaydailernvaikklsrpfqnqth
akrayrelvlmkcvnhkniigllnvftpqksleefqdvyivmelmdanlcqviqmeldhe
rmsyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglsfmmtvtryyrape
vilgmgykenvdlwsvgcimgemvchkilfpgrdyidqwnkvieqlgtpcpefmkklqpt
vrtyvenrpkyagysfeklfpdvlfpadsehnklkasqardllskmlvidaskrisvdea
lqhpyinvwydpseaeapppkipdkqlderehtieewkeliykevmd

Timeline for d3pzea_:

• d3pzea_ first appeared in SCOPe 2.01
  
• d3pzea_ appears in SCOPe 2.05
  
• d3pzea_ appears in SCOPe 2.07
  
• d3pzea_ appears in the current release, SCOPe 2.08