SCOPe 2.08: Domain d3pp1a1: 3pp1 A:62-382

Lineage for d3pp1a1 (3pp1 A:62-382)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (850 PDB entries)

8. Domain d3pp1a1: 3pp1 A:62-382 [183918]
   Other proteins in same PDB: d3pp1a2
   automated match to d1s9ja_
   complexed with act, atp, izg, mg

Details for d3pp1a1

PDB Entry: 3pp1, 2.7 Å

PDB Description: crystal structure of the human mitogen-activated protein kinase kinase 1 (mek 1) in complex with ligand and mgatp

PDB Compounds: (A:) Dual specificity mitogen-activated protein kinase kinase 1

SCOPe Domain Sequences for d3pp1a1:

Sequence, based on SEQRES records:

>d3pp1a1 d.144.1.7 (A:62-382) automated matches {Human (Homo sapiens) [TaxId: 9606]}
elkdddfekiselgagnggvvfkvshkpsglvmarklihleikpairnqiirelqvlhec
nspyivgfygafysdgeisicmehmdggsldqvlkkagripeqilgkvsiavikgltylr
ekhkimhrdvkpsnilvnsrgeiklcdfgvsgqlidsmansfvgtrsymsperlqgthys
vqsdiwsmglslvemavgrypipppdakelelmfgcqvegdaaetpprprtpgrplssyg
mdsrppmaifelldyivnepppklpsgvfslefqdfvnkcliknpaeradlkqlmvhafi
krsdaeevdfagwlcstigln

Sequence, based on observed residues (ATOM records):

>d3pp1a1 d.144.1.7 (A:62-382) automated matches {Human (Homo sapiens) [TaxId: 9606]}
elkdddfekiselgagnggvvfkvshkpsglvmarklihleikpairnqiirelqvlhec
nspyivgfygafysdgeisicmehmdggsldqvlkkagripeqilgkvsiavikgltylr
ekhkimhrdvkpsnilvnsrgeiklcdfgvsgqlidsmansfvgtrsymsperlqgthys
vqsdiwsmglslvemavgrypipppdakelelmfpmaifelldyivnepppklpsgvfsl
efqdfvnkcliknpaeradlkqlmvhafikrsdaeevdfagwlcstigln

Timeline for d3pp1a1:

• d3pp1a1 first appeared in SCOPe 2.01, called d3pp1a_
  
• d3pp1a1 appears in SCOPe 2.07