Lineage for d3pa4a_ (3pa4 A:)

  1. Root: SCOPe 2.02
  2. 1190016Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 1220003Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1220004Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1220070Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1220309Protein Cell cycle checkpoint kinase chk1 [64404] (1 species)
    CaMK group; CAMKL subfamily; serine/threonine kinase
  7. 1220310Species Human (Homo sapiens) [TaxId:9606] [64405] (42 PDB entries)
  8. 1220314Domain d3pa4a_: 3pa4 A: [183611]
    automated match to d1ia8a_
    complexed with c72, gol

Details for d3pa4a_

PDB Entry: 3pa4 (more details), 1.59 Å

PDB Description: X-ray crystal structure of compound 2a bound to human CHK1 kinase domain
PDB Compounds: (A:) Serine/threonine-protein kinase Chk1

SCOPe Domain Sequences for d3pa4a_:

Sequence, based on SEQRES records: (download)

>d3pa4a_ d.144.1.7 (A:) Cell cycle checkpoint kinase chk1 {Human (Homo sapiens) [TaxId: 9606]}
vedwdlvqtlgegaygevqlavnrvteeavavkivdmkravdcpenikkeicinkmlnhe
nvvkfyghrregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvylhgig
ithrdikpenlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellkrrefh
aepvdvwscgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsaplallhki
lvenpsaritipdikkdrwynkplkkg

Sequence, based on observed residues (ATOM records): (download)

>d3pa4a_ d.144.1.7 (A:) Cell cycle checkpoint kinase chk1 {Human (Homo sapiens) [TaxId: 9606]}
vedwdlvqtlgegaygevqlavnrvteeavavkivdmnikkeicinkmlnhenvvkfygh
rregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvylhgigithrdikp
enlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellkrrefhaepvdvws
cgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsaplallhkilvenpsar
itipdikkdrwynkplkkg

SCOPe Domain Coordinates for d3pa4a_:

Click to download the PDB-style file with coordinates for d3pa4a_.
(The format of our PDB-style files is described here.)

Timeline for d3pa4a_: