SCOPe 2.01: Domain d3okha_: 3okh A:

Lineage for d3okha_ (3okh A:)

1. Root: SCOPe 2.01

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (10 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (97 PDB entries)

8. Domain d3okha_: 3okh A: [183074]
   automated match to d1osha_
   protein/DNA complex; complexed with okh

Details for d3okha_

PDB Entry: 3okh, 2.5 Å

PDB Description: Crystal structure of human FXR in complex with 2-(4-chlorophenyl)-1-[(1S)-1-cyclohexyl-2-(cyclohexylamino)-2-oxoethyl]-1H-benzimidazole-6-carboxylic acid

PDB Compounds: (A:) Bile acid receptor

SCOPe Domain Sequences for d3okha_:

Sequence, based on SEQRES records:

>d3okha_ a.123.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
eltpdqqtllhfimdsynkqrmpqeitnkilkeafsaeenfliltematnhvqvlveftk
klpgfqtldhedqiallkgsaveamflrsaeifnkklpsghsdllearirnsgisdeyit
pmfsfyksigelkmtqeeyalltaivilspdrqyikdreaveklqeplldvlqklckihq
penpqhfacllgrltelrtfnhhhaemlmswrvndhkftpllceiwdv

Sequence, based on observed residues (ATOM records):

>d3okha_ a.123.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
eltpdqqtllhfimdsynkqrmpqeitnkilkeafsaeenfliltematnhvqvlveftk
klpgfqtldhedqiallkgsaveamflrsaeifnkklpsghsdllearirnsgisdeyit
pmfsfyksigelkmtqeeyalltaivilspdryikdreaveklqeplldvlqklckihqp
enpqhfacllgrltelrtfnhhhaemlmswrvndhkftpllceiwdv

Timeline for d3okha_:

• d3okha_ is new in SCOPe 2.01-stable
  
• d3okha_ appears in SCOPe 2.02
  
• d3okha_ appears in the current release, SCOPe 2.08