SCOPe 2.02: Domain d3noab_: 3noa B:

Lineage for d3noab_ (3noa B:)

1. Root: SCOPe 2.02

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48525] (76 PDB entries)
   Uniprot P37231 232-505

8. Domain d3noab_: 3noa B: [182439]
   automated match to d1fm6d_
   complexed with 5bc

Details for d3noab_

PDB Entry: 3noa, 1.98 Å

PDB Description: Crystal structure of human PPAR-gamma ligand binding domain complex with a potency improved agonist

PDB Compounds: (B:) Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d3noab_:

Sequence; same for both SEQRES and ATOM records:

>d3noab_ a.123.1.1 (B:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkh
itplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheii
ytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlai
fiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqiv
tehvqllqvikktetdmslhpllqeiykdly

Timeline for d3noab_:

• d3noab_ first appeared in SCOPe 2.01
  
• d3noab_ appears in SCOPe 2.03
  
• d3noab_ appears in the current release, SCOPe 2.08